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Drug Delivery
Formulation Development, Optimization, and Characterization of Entrectinib-Loaded Supersaturable…
Entrectinib is a novel potent anticancer drug with poor aqueous solubility. A supersaturable self-nanoemulsifying drug delivery system of entrectinib is developed using a super saturation promoter. The components of the isotropic mixture of SNEDDS were selected based on solubility and emulsification…
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Tubercular Drug Delivery Systems – Advances in Treatment of Infectious Diseases – Part…
The new book "Tubercular Drug Delivery Systems - Advances in Treatment of Infectious Diseases" book targets new advances in areas of treatment and drug delivery sciences for tuberculosis. It covers advances in drug therapy and drug targeting that focus on innovative trend defining technologies…
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Tubercular Drug Delivery Systems – Advances in Treatment of Infectious Diseases – Part…
The new book "Tubercular Drug Delivery Systems - Advances in Treatment of Infectious Diseases" book targets new advances in areas of treatment and drug delivery sciences for tuberculosis. It covers advances in drug therapy and drug targeting that focus on innovative trend defining technologies and…
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Utilization of experimental design in the formulation and optimization of hyaluronic acid–based…
Numerous problems affect oral health, and intensive research is focused on essential oil–based nanoemulsions that might treat prevent or these problems. Nanoemulsions are delivery systems that enhance the distribution and solubility of lipid medications to targeted locations. Turmeric (Tur)- and…
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Hydroquinone cream-based polymer microneedle roller for the combined treatment of large-area…
Melasma is a common hyperpigmented skin condition that occurs on the face and other areas prone to light exposure, seriously affecting people's quality of life. Microneedle, a new type of transdermal drug delivery device, can significantly improve skin permeability. In this study, we designed and…
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Ocular Drug Delivery: a Comprehensive Review
The human eye is a sophisticated organ with distinctive anatomy and physiology that hinders the passage of drugs into targeted ophthalmic sites. Effective topical administration is an interest of scientists for many decades. Their difficult mission is to prolong drug residence time and guarantee an…
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Skin drug delivery using lipid vesicles: A starting guideline for their development
Lipid vesicles can provide a cost-effective enhancement of skin drug absorption when vesicle production process is optimised. It is an important challenge to design the ideal vesicle, since their properties and features are related, as changes in one affect the others. Here, we review the main…
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Polymeric Systems for the Controlled Release of Flavonoids
Flavonoids are natural compounds that are attracting great interest in the biomedical field thanks to the wide spectrum of their biological properties. Their employment as anticancer, anti-inflammatory, and antidiabetic drugs, as well as for many other pharmacological applications, is extensively…
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Apisolex™ Polymer – by Lubrizol
Solubility-enhancing polymer for use in bolus injections and IV infusions
Lubrizol Life Science Health’s (LLS Health’s) Apisolex™ GMP, injectable-grade excipient is a safe, polyamino acid-based polymer that enhances the solubility of BSC Class II and IV APIs.
Formulation Benefits…
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Enhancing the oral drug delivery through hot melt extrusion techniques
Hot melt extrusion has been developed as a fresh technique for taste masking, in recent years. This method provides many aids as compared to traditional methods like avoiding the use of solvents, continuous manufacturing, ease to scale up, and adaptability to meet the goals of FDA for quality…
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