Browsing Category
Drug Delivery
Liposomes: Bridging the gap from lab to pharmaceuticals
Abstract
Liposomes are versatile and effective drug delivery systems, as highlighted by various medical applications. Their well-defined bilayer structure is suited for the encapsulation of drugs with diverse chemical properties and for a variety of release strategies. Understanding liposome…
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Lipid Nanovesicles for Antioxidant Delivery in Skin: Liposomes, Ufasomes, Ethosomes, and Niosomes
Abstract
The skin, being the largest organ of the human body, serves as the primary barrier against external insults, including UV radiation, pollutants, and microbial pathogens. However, prolonged exposure to these environmental stressors can lead to the generation of reactive oxygen species…
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Clinical Trial: Safety and Efficacy of a Novel Oesophageal Delivery System for Topical…
ABSTRACT
Background
EsoCap is a thin mucoadhesive film designed to target the oesophageal mucosa. The device loaded with mometasone furoate (ESO-101) is under investigation for the treatment of eosinophilic oesophagitis (EoE).
Aims
To evaluate the efficacy, safety and tolerability of…
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PhytoSquene® plant-based, pharma-grade squalene for vaccine adjuvants
Preserving biodiversity and ensuring safety with non-animal-derived squalene in pharma quality
PhytoSquene® is our non-animal-derived squalene that can be used in vaccines and other pharmaceutical applications. This alternative to animal-derived squalene has many benefits. PhytoSquene®…
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Core-shell aerogel design for enhanced oral insulin delivery
Abstract
Current protein-based therapies often rely on intravenous and subcutaneous injections leading to patient discomfort due to the need for frequent administration. Oral administration route presents a more patient-friendly alternative, but overcoming the challenge of low drug…
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Sublingual permeability of model drugs in New Zealand White Rabbits: In Vitro-In vivo correlation
Abstract
This study investigated sublingual drug permeation and administration using five model drugs with diverse physicochemical properties, employing New Zealand White Rabbit sublingual mucosa for in vitro experiments and New Zealand White Rabbits for in vivo studies. The research aimed to…
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Leveraging machine learning to streamline the development of liposomal drug delivery systems
Abstract
Drug delivery systems efficiently and safely administer therapeutic agents to specific body sites. Liposomes, spherical vesicles made of phospholipid bilayers, have become a powerful tool in this field, especially with the rise of microfluidic manufacturing during the COVID-19 pandemic.…
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Evaluating Various Lactose Types as Solid Carriers for Improving Curcumin Solubility in Solid…
Abstract
Curcumin, a bioactive compound derived from turmeric, possesses numerous pharmaceutical properties; however, its poor aqueous solubility and permeability result in low bioavailability. This study aims to develop a solid self-nanoemulsifying drug delivery system (S-SNEDDS) using different…
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Bisoprol-Excipient Compatibility Studies For Advanced Drug Delivery Systems Development
Fast dissolving drug delivery systems offers a solution for pediatric, geriatric, mentally ill people and those patients having difficulty in swallowing tablets or capsules. In the present study, an attempt had been made to prepare fast dissolving tablets of Bisoprolol Fumarate, an antihypertensive…
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EUDRACAP® functional, ready-to-fill coated capsules for fast oral drug development
From optimized gastric resistance to enhanced bioavailability - EUDRACAP® leverages the functional versatility and safety of EUDRAGIT® to solve key challenges in oral drug delivery.
Pharmaceutical companies launching new oral drugs need the right coated capsule formulation to enhance performance…
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