Logo Meldepharm

Experts on High Precision R&D Tableting Instruments
and powder characterization


Mission: R&D instruments Made by people For people

MEDELPHARM stands for a symbiosis of intimate understanding of powder tableting behavior and innovative tableting technologies that provide knowledge required by the industry. Thanks to the knowledge of production processes, formulators’ needs and technology, MEDELPHARM keeps creating new generations of tableting instruments to expand possibilities for all scientists.

Markets and Industries: Powder, Powder everywhere

For the last 115 years, tablets have been produced in all shapes, sizes and can be found everywhere in your life:

  • Pharmaceutical
  • Food & Confectionary
  • Cosmetics
  • Chemistry & Detergent
  • Batteries & Catalyst
  • Explosive & Nuclear

See Medelpharm´s revolutionary benchtop R&D tablet press STYL’One Nano

STYL’One Evo
STYL’One Evo

Product Overview:

STYL’One Evo

The STYL’One Evo is the most versatile single-punch tableting press for Research & Development, scale-up and production support. This allpurpose tableting instrument enables fast API characterization and single layer to multi-layer formulation development. Develop your formulation at full production speed with only a few grams of powder!


Fully instrumented, the STYL’One Evo is a real “tableting robot” to explore the design space (QbD) and analyze your formula with utmost efficiency. It is flexible with many modules and accessories to fit your needs. Several safety options are available depending on the potency of API you use.

Technical highlights:
  • Force mode for cost-saving on API characterization
  • Target thickness to mimic rotary tablet press
  • Manual, advanced gravity and force feeding options
  • Multi-layer up to five layers with three products
  • Automatic core feeding system for tab-in-tab
  • Replication of all types of rotary tablet presses
  • Roll compaction mimicking for ultimate material sparing
  • Can be upgraded to production standards (GMP) with external lubrication

STYL’One Nano

The STYL’One Nano by Medelpharm is the revolutionary benchtop R&D tablet press for demanding formulation scientists with price performance in mind. Characterize your API and develop your single layer formulation with only a few grams of powder!

STYLOne Nano
STYLOne Nano

Technical Highlights:

  • Benchtop model compact and mobile with a small footprint
  • Driven by Alix, the most powerful integrated R&D software platform
  • Force, displacement and radial measurements
  • Bottom punch dynamics similar to the movements of a rotary press
  • Designed with USP <1062> in mind (square, V-shape, pre- and main compression)
  • Force mode for cost-saving on API characterization
  • Target thickness to mimic small turret rotary tablet press
  • Manual, advanced gravity and force feeding options
  • Easy to handle – Easy to clean

See the product brochures and technical datasheets of both products:

STYL’One Evo product brochure


STYL’One Evo technical data sheet


Material Characterization


STYL’One Nano product brochure


STYL’One Nano technical datasheet


ROCO: KP Fitting


STYL’One Contained Executions

Powders being more and more potent has made a higher level of protection essential to ensure operator safety.

The STYL’One series provides three operator safety configurations which differ in specifications, technology and budget:


All STYL’One are easy to clean and produce tablets with minimal amount of active material in the compaction area. The standard vacuum system keeps the compaction area clean and under negative pressure, limiting the exposure for the operator.
STYL’One Nano and STYL’One Evo can also be placed in a laminar flow booth or bench for user protection.

(click picture to enlarge)

Dry containment – OEB 3 execution

STYL’One Evo OEB 3 has been designed to add an extra layer of safety by limiting operator exposure to airborne particles during operation. Negative pressure generation and monitoring as well as relevant entry and exit ports will allow the operator to manipulate samples safely without compromising performances. Vacuum and manual control of air flow ensure that the machine is permanently under negative pressure. STYL’One Evo OEB 3 can also be safely operated in a non-contained mode when manipulating non-hazardous material.

Wet containment – OEB 5 execution

(click picture to enlarge)

When using Highly-Potent API, a full OEB5 containment solution with isolator can be deployed for both R&D and GMP applications. The negative pressure control and monitoring combined with air filtration and safe cleaning reduce drastically the operator exposure. The tablet press can safely run while the operator performs other tasks inside the contained chamber like weighing, hardness measurements or cleaning. The STYL’One Evo Contained can also be safely operated with the isolator open when manipulating non-hazardous material.



615 rue du Chat Botté, ZAC des Malettes
F-01700 Beynost, France