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Pediatric-friendly suspension for oral administration of pyrimethamine in congenital toxoplasmosis: Development and in use-stability study
Abstract
This study focused on developing and assessing the stability of pyrimethamine (PYM) sugar-free oral suspensions for treating congenital toxoplasmosis in the pediatric population, including neonates. Extemporaneous suspensions (2 mg/mL) were prepared using carboxymethylcellulose (CMC) or…