Gelatin is a versatile and widely used ingredient in the pharmaceutical industry, where it serves various critical functions in the formulation and production of pharmaceutical products. This article explores the sources, manufacturing process, and applications of pharmaceutical gelatin, shedding light on its significance in pharmaceuticals.
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Gelatin
The effect of excipients on oral lyophilizates quality attributes
Pharmaceutical industry is constantly focused on researching patient-centered dosage forms that can maximize the therapeutic potential of an active pharmaceutical ingredient, as for example orodispersible form. The main advantage of orodispersible dosage forms is that they are suitable for patients…
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Continuous Manufacturing of Solvent-Free Cyclodextrin Inclusion Complexes for Enhanced Drug…
Conventional cyclodextrin complexation enhances the solubility of poorly soluble drugs but is solvent-intensive and environmentally unfavorable. This study evaluated solvent-free hot-melt extrusion (HME) for forming cyclodextrin inclusion complexes to improve the solubility and dissolution of…
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Electrospun composite nanofibers for treating infectious esophagitis
The electrospinning technique enables the convenient fabrication of non-woven fibrous materials with excellent properties such as fine diameters, a large surface area per unit mass, high porosity, high gas permeability, and small pore sizes. Nanofiber applications in healthcare systems continue to…
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Multilayer 3D bioprinting and complex mechanical properties of alginate-gelatin mesostructures
Abstract
In the biomedical field, extrusion-based 3D bioprinting has emerged as a promising technique to fabricate tissue replacements. However, a main challenge is to find suitable bioinks and reproducible procedures that ensure good printability and generate final printed constructs with high…
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Comparison of the Behavior of 3D-Printed Endothelial Cells in Different Bioinks
Biomaterials with characteristics similar to extracellular matrix and with suitable bioprinting properties are essential for vascular tissue engineering. In search for suitable biomaterials, this study investigated the three hydrogels alginate/hyaluronic acid/gelatin (Alg/HA/Gel), pre-crosslinked…
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Soft capsule technology: modified pea starch as a vegetal origin alternative to gelatin in capsule…
Introduction
Gelatin has been used as shell polymer in the manufacture of soft gelatin capsules (softgels) for about the past century. Its rheological and thermal properties offer adequate balance for subsequent process steps including gel solution preparation/transportation, film casting, and…
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Ocular application of electrospun materials for drug delivery and cellular therapies
The constraints of delivering conventional drugs, biologics and cell-based therapeutics to target ocular sites necessitate the fabrication of novel drug delivery systems to treat diverse ocular diseases. Conventional ocular drug delivery approaches are prone to low bioavailability, poor penetration…
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Solid implantable devices for sustained drug delivery
Implantable drug delivery systems (IDDS) are an attractive alternative to conventional drug administration routes. Oral and injectable drug administration are the most common routes for drug delivery providing peaks of drug concentrations in blood after administration followed by concentration decay…
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Microneedles for Enhanced Topical Treatment of Skin Disorders: Applications, Challenges, and…
Microneedles (MNs) can be used for the topical treatment of skin disorders as they directly deliver therapeutics to the site of skin lesions, resulting in increased therapeutic efficacy while having minimum side effects. MNs are used to deliver different kinds of therapeutics (e.g., small molecules,…
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PLGA – A versatile copolymer for design and development of nanoparticles for drug delivery
Introduction
Poly (lactic-co-glycolic acid) or PLGA, a highly hydrophobic copolymer comprised of lactic acid and glycolic acid, has been approved in many drug products and medical devices.1 Over the years since the first approved in 1997, PLGA has been widely studied polymer in the industry because…
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