Alteration of gel point of poloxamer 338 induced by pharmaceutical actives and excipients

19. January 2025

Abstract Poloxamer 338 is used as versatile thermo-responsive gelling agent in topical and sub-cutaneous applications. Due to application specific needs...

Permeation Enhancer in Microemulsions and Microemulsion-Based Gels: A Comparison of Diethylene Glycol Monoethyl Ether and Oleyl Alcohol

18. January 2025

Abstract Microemulsions have been commonly used with various permeation enhancers to improve permeability through the skin. The purpose of this...

Topical Application of Dipyridamole and Roflumilast Combination Nanoparticles Loaded Nanoemulgel for the Treatment of Psoriasis in Rats

21. December 2024

Abstract Background: Phosphodiesterase-4 is an enzyme that regulates immune responses and contributes to the development of psoriasis. Dipyridamole and roflumilast...

Evaluation of Topical Anti-Inflammatory Potential of Mentha piperita L. Extract by Formulation of Microemulgel

20. September 2024

ABSTRACT Background The present study is designed to develop a novel dosage form i.e. microemulgel which will enhance the rate...

Design, Optimization, and Characterization of Zolmitriptan Loaded Liposomal Gels for Intranasal delivery for acute migraine therapy

23. July 2024

Zolmitriptan is the primary drug for the treatment of Migraine. However, the bioavailability of the drug is low and requires...

Microemulsion-Based Polymer Gels with Ketoprofen and Menthol: Physicochemical Properties and Drug Release Studies

11. July 2024

Abstract Ketoprofen is a non-steroidal, anti-inflammatory drug frequently incorporated in topical dosage forms which are an interesting alternatives for oral...

Figure 1. SAOS measurements of the Ultrez 10 microgel submitted to different sonication times, (a) |G* | as a function of the oscillating stress; (b) G' and G" as functions of the oscillating stress; at 6.28 rad/s. (c) G' and G" as functions of the angular frequency at 3 Pa.

Influence of Sonication on the Molecular Characteristics of Carbopol® and Its Rheological Behavior in Aqueous Dispersions and Microgels

17. June 2024

Abstract The effect of sonication on the molecular characteristics of poliacrylic acid (Carbopol® Ultrez 10) and its rheological behavior in...

Formulating pharmaceutical topical dosage forms with high level of solvents and minimal quantity of water

10. June 2024

Poster presented by Gattefosse and RCPE at the 14th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical (PBP) Technology, 18 -...

Formulation development of nanostructured lipid carrier-based nanogels encapsulating tacrolimus for sustained therapy of psoriasis

10. May 2024

The goal of this study was to formulate tacrolimus nanogel based on nanostructured lipid carrier (NLC) in order to improve...

High mobility group box 1 cytokine targeted topical delivery of resveratrol embedded nanoemulgel for the management of atopic dermatitis

10. April 2024

Resveratrol is a polyphenolic compound showing anti-inflammatory activity by inhibition of high mobility group box 1 cytokine responsible for the...

Gelling agent