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Gelling agent
Anti-Inflammatory Drug Repurposing for Intranasal Delivery: Ketoprofen Nanoemulgel Development for…
The anti-inflammatory drug ketoprofen has shown promising results in the field of drug repurposing for the treatment of brain cancer, but currently developed formulations are for invasive administration (intravenous) and have very limited drug strength. Hence, the purpose of this work was to develop…
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Cyclodextrins and derivatives in drug delivery: New developments, relevant clinical trials, and…
Cyclodextrins (CD) and derivatives are functional excipients that can improve the bioavailability of numerous drugs. Because of their drug solubility improving properties they are used in many pharmaceutical products. Furthermore, the stability of small molecular drugs can be improved by the…
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Overcoming Challenges of Taste Masking
In a 2003 survey conducted by the American Association of Pediatrics, unpleasant taste was identified as the most significant barrier to completing treatment in pediatrics.
Drug taste masking is extremely relevant to improve patient convenience and compliance. It's currently a relevant…
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Development, evaluation and recent progress of ocular in situ gelling drug delivery vehicle based on…
Abstract
The fabrication of an effective in situ gelling ophthalmic drug delivery vehicle is recently received enormous interest to overcome the demerits of conventional ocular solutions and achieve desired therapeutic efficacy. Poloxamer 407 and poloxamer 188 are among the most commonly used…
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Formulation Design and characterization of Antifungal Emulgel for Topical Delivery
Emulgel is the latest generation in novel drug transport device used for manage launch of emulsion and gel for the reason of topical use. The steadiness of emulsion is increased, while it is integrated into gel. Miconazole is an antifungal drug has been used inside the remedy of dermatophytic…
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QbD Design, Formulation, Optimization and Evaluation of Trans-Tympanic Reverse Gelatination Gel of…
Traditional otic drug delivery methods lack controlled release capabilities, making reverse gelatination gels a promising alternative. Reverse gelatination gels are colloidal systems that transition from a sol to a gel phase at the target site, providing controlled drug release over an extended…
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Orthogonal Gelations to Synthesize Core–Shell Hydrogels Loaded with Nanoemulsion-Templated Drug…
Hydrophobic active pharmaceutical ingredients (APIs) are ubiquitous in the drug development pipeline, but their poor bioavailability often prevents their translation into drug products. Industrial processes to formulate hydrophobic APIs are expensive, difficult to optimize, and not flexible enough…
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In Vitro and In Vivo Efficacy of Topical Dosage Forms Containing Self-Nanoemulsifying Drug Delivery…
The external use of curcumin is rare, although it can be a valuable active ingredient in the treatment of certain inflammatory diseases. The aim of our experimental work was to formulate topical dosage forms containing curcumin for the treatment of atopic dermatitis. Curcumin has extremely poor…
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Development and Characterization of Pentaerythritol-EudragitRS100 Co-processed Excipients as Solid…
Abstract
Atorvastatin (ATV), a lipid-lowering agent, has low oral bioavailability due to its poor water solubility, permeability, and low dissolution rate. Therefore, pentaerythritol-EudragitRS100 co-processed excipients (PECE) were synthesized, and their feasibility as solid dispersion carriers…
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