Granulation

Situation One of our customers developed 3 different dosages for 1 active pharmaceutical ingredient (API). Coating was avoided as the...

Why developing sustained release formulations? Why developing sustained release formulations? Sustained release (SR) pharmaceutical formulations are built to deliver a...

FROM CHALLENGE TO TRIUMPH Formulating a 500 mg chewable Vitamin C tablet proved especially difficult due to the ingredient’s poor...

Abstract Real-time monitoring of particle size distribution (PSD) in fluidized bed granulation remains a significant challenge due to the complex...

Abstract Roller compaction dry granulation is one of the pivotal dry granulation technologies in solid dosage form manufacturing, offering irreplaceable...

Introduction Roller compaction/dry granulation (RC/DG) is a key process in pharmaceutical manufacturing as it improves powder flowability, density, and segregation...

Focused on your needs – BASF solutions for the pharmaceutical industry BASF produces excipients and active ingredients of outstanding quality...

Abstract The commercial implementation of continuous granulation requires an intelligent control framework compliant with Quality by Design (QbD) principles. To...

Abstract Purpose This study aimed to optimize a high-shear hot-melt granulation process for the development of tinidazole 500 mg tablets while...

Abstract Despite their widely recognized performance-related benefits, nanosuspensions (NSs) present major challenges, mainly due to their poor stability during storage....