Granulation

Abstract Background: Polyols are widely used as tablet diluents due to their high solubility, favourable taste, and ability to form...

Abstract Wet granulation-a unit operation involving mixing polymeric binders with powdered formulations-is well established in the pharmaceutical industry, playing a...

Abstract Roller compaction is often utilized as the first step to improve flow properties and homogeneity of pharmaceutical mixtures. Since...

Abstract Background/Objective: The high-shear granulator is considered an effective piece of equipment for layering pelletization because it enhances drug amorphization and...

Abstract The transition from traditional batch to continuous pharmaceutical manufacturing puts additional demands on the efficient process development and operation....

Abstract The presence of N-nitrosamine impurities and nitrosamine drug substance-related impurities (NDSRIs) in medicines poses a significant challenge not only for...

Transforming Pharmaceutical Manufacturing Introduction In the pharmaceutical industry, efficiency and quality are crucial. Direct compression has emerged as a revolutionary...

Abstract Granulation is a major focus of pharmaceutical R&D, as a key step in the development of solid pharmaceuticals. In...

Abstract Regime maps are vital in twin-screw granulation, predicting outcomes via dimensionless numbers. This study develops a novel regime map...

Abstract Amorphous solid dispersions (ASDs) represent a promising formulation strategy for improving the solubility and bioavailability of poorly water-soluble drugs,...