Lipids

Abstract Lipid nanoparticles (LNPs) administered parenterally often show poor localization to multiple tissue types, including the pancreas and gastrointestinal (GI)...

Abstract The present study aimed to develop and optimize a shikonin-loaded mucoadhesive microemulsion for intranasal delivery with the objective of...

Abstract Drug-excipient interaction studies are fundamental for the efficient development of new formulations. These interactions directly influence drug stability, loading...

Abstract Lipid-based formulations (LBFs) offer a promising strategy to enhance the oral bioavailability of poorly water-soluble drugs, such as biopharmaceutical...

Abstract Curcumin has considerable therapeutic potential; however, its poor solubility and permeability limit its clinical applications. We evaluated menthol-based hydrophobic...

Understanding how to optimize hyaluronic acid in lipid-based formulations is a key focus for skincare formulators. Hyaluronic acid (HA) and...

Discover together with IOI Oleo at CPHI Milan what the next generation of lipid-based excipients can achieve. The CPHI is...

Abstract This study presents a Quality by Design (QbD) strategy combined with Design of Experiments (DoE) to develop hybrid polymer–lipid hot-melt extruded (HME) formulations...

Abstract Madecassoside, a major triterpenoid glycoside from Centella asiatica, has potential value for dermatological applications; however, its poor stratum corneum permeability...

Abstract Sorafenib is an orally administered multikinase inhibitor whose clinical utility is limited by extremely low aqueous solubility and poor...