Lipids

Discover together with IOI Oleo at CPHI Milan what the next generation of lipid-based excipients can achieve. The CPHI is...

Abstract This study presents a Quality by Design (QbD) strategy combined with Design of Experiments (DoE) to develop hybrid polymer–lipid hot-melt extruded (HME) formulations...

Abstract Madecassoside, a major triterpenoid glycoside from Centella asiatica, has potential value for dermatological applications; however, its poor stratum corneum permeability...

Abstract Sorafenib is an orally administered multikinase inhibitor whose clinical utility is limited by extremely low aqueous solubility and poor...

Abstract Glioblastoma is one of the aggressive and hard-to-treat forms of brain tumor, and this is largely due to the...

Abstract Liquisolid systems (LSS) represent a promising approach for improving dissolution of poorly water-soluble drugs; however, the interplay between formulation...

This article is part of the “Less Known Facts About Excipients” series by Philippe Tschopp. Carnauba Wax Excipient: Palm Origin,...

Abstract Background: Lipid nanoparticles are widely investigated as oral drug delivery systems, but their intestinal performance remains difficult to predict based...

Abstract This study optimized the formulation parameters of nanostructured lipid carriers (NLCs) loaded with Origanum vulgare L. essential oil (OEO), produced by...

Abstract Although solid oral dosage forms are widely used in adult drug therapy, age-appropriate formulations for pediatric patients remain limited....