Lipids

Abstract Sorafenib is an orally administered multikinase inhibitor whose clinical utility is limited by extremely low aqueous solubility and poor...

Abstract Glioblastoma is one of the aggressive and hard-to-treat forms of brain tumor, and this is largely due to the...

Abstract Liquisolid systems (LSS) represent a promising approach for improving dissolution of poorly water-soluble drugs; however, the interplay between formulation...

This article is part of the “Less Known Facts About Excipients” series by Philippe Tschopp. Carnauba Wax Excipient: Palm Origin,...

Abstract Background: Lipid nanoparticles are widely investigated as oral drug delivery systems, but their intestinal performance remains difficult to predict based...

Abstract This study optimized the formulation parameters of nanostructured lipid carriers (NLCs) loaded with Origanum vulgare L. essential oil (OEO), produced by...

Abstract Although solid oral dosage forms are widely used in adult drug therapy, age-appropriate formulations for pediatric patients remain limited....

Abstract In the pediatric patient group, there is a constant need for individualized dosage forms with precise and adjustable drug...

Lipid-based excipients from IOI Oleo help to improve the bioavailability of poorly soluble active ingredients. The majority of new active...

Abstract Cannabidiol (CBD) exhibits poor oral bioavailability (approximately 6%) due to low solubility and excessive first-pass metabolism, limiting its therapeutic...