Dry Powder Inhalers (DPI)

Introduction In the realm of pharmaceutical formulations, excipients are indispensable, enhancing the safety, efficacy, stability, manufacturability, and patient acceptability of...

Abstract Pulmonary delivery of poorly water-soluble drugs is constrained by the limited volume of epithelial lining fluid, heterogeneous aerosol deposition,...

Abstract As a major public health issue, chronic obstructive pulmonary disease (COPD) causes approximately 2.7 million deaths worldwide each year...

Abstract Capsule aperture geometry is a tunable design parameter that can markedly influence powder emission and aerosol dispersion in capsule-based...

Abstract Inhaled biologics to treat lung diseases have an extensive history. This is counterbalanced by the limited products that have...

Abstract Purpose To overcome the strong inter-particulate interactions between the drug and carrier in dry powder inhalers (DPIs), an amorphous...

Abstract Inhaled protein therapeutics offer a direct route to the lung and hold strong promise for improving respiratory disease treatment....

Abstract In this paper, the International Pharmaceutical Aerosol Consortium on Regulation and Science (IPAC-RS), discusses the current regulatory landscape associated...

Abstract This research evaluated the viability of powder discharge-based KinetiSol (pKSD) as a rapid, solvent-free particle engineering technology for producing...

From Milk to Medicine: 100 Years of Pharmaceutical Lactose continuous improvement For more than a century, lactose has quietly shaped...