Dry Powder Inhalers (DPI)

World Asthma Day takes place every year on the first Tuesday of May and will be held for the 26th time in 2023. The day was initiated as a global initiative led by the Global Initiative for Asthma (GINA) in collaboration with health care groups and asthma educators to raise global awareness about…
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The specifications of excipients are important to pharmaceutical manufacturers to ensure that the final product can be manufactured robustly over the entire lifecycle of a drug product. Particle size specifications are key for dry powder inhalation excipients and they should be agreed between users…
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Co-amorphous systems (COAMS) have raised increasing interest in the pharmaceutical industry, since they combine the increased solubility and/or faster dissolution of amorphous forms with the stability of crystalline forms. However, the choice of the co-former is critical for the formation of a…
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Surface roughness of carrier particles can impact dry powder inhaler (DPI) performance. There are opposing views on the effect of roughness on DPI performance. Hence, a systematic approach is needed to modify carrier surfaces and evaluate the impact on drug delivery. Carrier particle surfaces were…
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Dry powder inhalers (DPIs) can be used with a wide range of drugs such as small molecules and biologics and offer several advantages for inhaled therapy. Early DPI products were intended to treat asthma and lung chronic inflammatory disease by administering low-dose, high-potency drugs blended with …
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N-acetylcysteine (NAC) has both antioxidant and immunomodulatory activities and has been used as adjuvant therapy in several viral infections. Recently, NAC attracted attention for its possible role in reducing the affinity of the spike protein receptor binding domain to angiotensin-converting…
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The surface of particles is the hotspot of interaction with their environment and is therefore a major target for particle engineering. Particles with tailored coatings are greatly desired for a range of different applications. Amorphous coatings applied via film coating or microencapsulation have…
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The LUND University Sweden, Emmercon and the Swedish Foundation for Strategic Research proudly present the following study: The Match Between Adhesive Mixture Formulation And Device INTRODUCTION This study investigates whether it is the formulation or the device that is key to the…
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Kiel University, Germany, and  Meggle GmbH & Co. KG present "A functional study of tubing material for the spray drying of mRNA-lipoplexes": INTRODUCTION The overall aim of this project is the development of an inhalable dry powder platform for mRNA vaccines. As many viral infections…
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Dry powder inhalation therapy has been effective in treating localized lung diseases such asthma, chronic obstructive pulmonary diseases (COPD), cystic fibrosis and lung infections. In vitro characterization of dry powder formulations includes the determination of physicochemical nature and aerosol…
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