HPMC - Hydroxypropylmethylcellulose

Abstract Amorphous solid dispersions (ASDs) are widely used to enhance the solubility of poorly water-soluble drugs. Among commercial manufacturing approaches,...

Abstract Biomacromolecules including peptides, proteins, antibodies, and gene medicines, comprise important classes of therapeutics in treating disease. A drawback of...

Abstract This research evaluated the viability of powder discharge-based KinetiSol (pKSD) as a rapid, solvent-free particle engineering technology for producing...

Abstract Curcumin has been widely reported to exhibit anticancer potential; however, its clinical application is limited by poor aqueous solubility...

Abstract This study aimed to develop an innovative pediatric-friendly fixed-dose combination (FDC) of omeprazole (OMZ) and domperidone (DOM) for the...

Abstract Hygroscopicity poses a significant challenge in the formulation of pharmaceutical and nutraceutical products, as moisture absorption often leads to...

Abstract Four decades have elapsed since orally disintegrating tablets (ODTs) were first formulated as the emulsion/type Lyoc tablet, a porous...

Abstract This study addresses a critical challenge in delivering a drug to prevent angina in the early morning hours, aligning...

Abstract Spray dried dispersion (SDD) is increasingly used in solid dose formulations for poorly soluble active pharmaceutical ingredients (APIs). Dissolution...

Abstract Objectives This study aims to investigate the effect of compaction pressure, coating polymer, pellet core, and spatial arrangement on...