HPMC - Hydroxypropylmethylcellulose

Abstract The tabletability flip phenomenon (TFP), in which a solid form of an active pharmaceutical ingredient (API) with lower inherent...

Abstract Microwave-induced in situ amorphization is an innovative technology that enables the direct preparation of amorphous solid dispersions (ASDs) in the final...

Abstract Amorphous solid dispersions (ASD) are an effective strategy to enhance the solubility of poorly water-soluble drugs. Hot melt extrusion...

Abstract Cyclodextrins (CDs) have traditionally been recognized as excipients that enhance solubility and stability of drugs. However, growing evidence shows...

Abstract This study aimed to develop a scalable, coating-free delayed-release matrix tablet via twin-screw melt granulation (TSMG) using Eudragit® FS100...

Abstract The pharmaceutical industry is increasingly adopting co-processed excipients as alternatives to conventional excipients in tablet manufacturing despite certain regulatory...

Abstract Fenofibric acid (FA), the active metabolite of fenofibrate, is a potent lipid-modifying agent whose clinical effectiveness is often compromised...

Abstract Magnesium stearate (MgSt) has been used as a force control agent (FCA) to enhance the aerosol performance of carrier-based...

Abstract Background: Solid dispersions (SDs) of etodolac (ETD), a poorly water-soluble drug model, were developed to enhance its solubility and dissolution...

Abstract Famotidine suffers from low oral bioavailability due to poor aqueous solubility, short half-life, and limited gastric retention. This study...