PAT

Abstract The increasing demand for nondestructive quantification of active pharmaceutical ingredients in low-dose formulations has highlighted the sensitivity limitations of...

Abstract Quality by design (QbD) and design of experiments (DoE) have become central to modern pharmaceutical development, yet most guidance...

Spin freeze-drying (SFD) has emerged as a potential breakthrough in pharmaceutical lyophilization. It promises over 90 % reductions in cycle time...

Amorphous solid dispersions (ASDs) enhance the solubility and bioavailability of drugs, yet their inherent instability and the risk of recrystallisation...

Abstract Purpose This study aims to develop an integrated control strategy using process analytical technology (PAT) and a quality by...

Abstract The integration of Process Analytical Technology (PAT) into pharmaceutical process development has become a critical focus since the issuance...

Abstract Process analytical technology (PAT) tools are an important part of process monitoring and control in pharmaceutical continuous manufacturing (CM)...

Abstract Process Analytical Technology (PAT) plays a crucial role in the design of today’s manufacturing lines as continuous manufacturing becomes...

Abstract Process Analytical Technology (PAT) has revolutionized pharmaceutical manufacturing by providing real-time monitoring and control capabilities throughout the production process....

Abstract Continuous manufacturing is gaining increasing interest in the pharmaceutical industry, also requiring real-time and non-destructive quality monitoring. Multiple studies...