Petrochemicals

Abstract Polymer nanoparticles (PNPs) are compact particulate systems typically ranging from 10 to 1000 nm in size and have emerged...

Abstract Background/Objectives: The development of extended-release oral dosage forms remains a complicated and time consuming process, particularly during early formulation...

Abstract This study explores the impact of drug loading (DL) on the physical stability, dissolution performance, and micellisation behaviour of...

Abstract Poor tablet hardness and drug re-crystallization are two common challenges of amorphous solid dispersion (ASD) formulations prepared with hot-melt...

Abstract Background/Objectives: Poor aqueous solubility of active pharmaceutical ingredients (APIs) remains a critical barrier to effective oral formulation. This study...

Abstract Therapeutic agents approved for the topical treatment of dermatological diseases have diverse physicochemical properties, but they are frequently poorly...

Abstract Ionizable aminolipids enable lipid nanoparticles (LNPs) to encapsulate nucleic acids at neutral pH and to release their cargo upon...

Abstract The aim of this study was to develop a once-daily controlled-release (CR) apixaban (APX) formulation that enhances bioavailability through...

Abstract The presented work investigates critical aspects of rational formulation design through machine learning (ML) methodology to identify essential patterns...

Abstract Tablet mechanical strength is governed by both the intrinsic mechanical properties of the constituent materials and the applied compaction...