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Abstract Background/Objectives: Poor aqueous solubility of active pharmaceutical ingredients (APIs) remains a critical barrier to effective oral formulation. This study...
Abstract Therapeutic agents approved for the topical treatment of dermatological diseases have diverse physicochemical properties, but they are frequently poorly...
Abstract Ionizable aminolipids enable lipid nanoparticles (LNPs) to encapsulate nucleic acids at neutral pH and to release their cargo upon...
Abstract The aim of this study was to develop a once-daily controlled-release (CR) apixaban (APX) formulation that enhances bioavailability through...
Abstract The presented work investigates critical aspects of rational formulation design through machine learning (ML) methodology to identify essential patterns...
Abstract Tablet mechanical strength is governed by both the intrinsic mechanical properties of the constituent materials and the applied compaction...
Abstract Effective dry-state stabilization of bacteriophages is crucial for expanding their therapeutic use. This study builds on previous findings that...
Abstract The toxicological evaluation of excipients plays a crucial role in the development of SEDDS. This study examined key formulation...
Abstract Background: Phytocannabinoids such as cannabidiol (CBD) and cannabigerol (CBG) have received increasing attention in the context of inflammatory and...
Abstract Hospital pharmacies are not equipped to produce lipid nanoemulsions, which are generally obtained using high-energy processes. This study reports...
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