Petrochemicals

Abstract The development of a robust oral solid dosage form requires knowledge of all the sources of variation that could...

Abstract The current work uses liquisolid (LS) technology to increase the absorption efficiency and dissolution rate of the weakly water-soluble...

Abstract Oral administration of solid dosage forms for delivery of therapeutic peptides is highly desired. Preclinical investigations on co-administration with...

Abstract PROTACs are an emerging class of beyond-rule-of-5 molecular drugs currently under clinical investigation for the treatment of malignant diseases...

Abstract The study of extractables and leachables has become increasingly important in the pharmaceutical industry, with growing concerns about minimizing...

Abstract Granulation is a major focus of pharmaceutical R&D, as a key step in the development of solid pharmaceuticals. In...

Abstract Polymeric amorphous solid dispersions (ASDs) are frequently used to improve solubility and oral bioavailability of poorly water-soluble drugs. The...

Abstract Ezetimibe is a cholesterol absorption inhibitor widely used in the treatment of dyslipidemia. However, its clinical efficacy is limited...

Abstract Regime maps are vital in twin-screw granulation, predicting outcomes via dimensionless numbers. This study develops a novel regime map...

Abstract Amorphous solid dispersions (ASDs) represent a promising formulation strategy for improving the solubility and bioavailability of poorly water-soluble drugs,...