Quality by Design (QbD)

The Role of Pellets in Advanced Oral Drug Delivery Formulation and design of multiunit particulate systems play a central role...

Abstract Modern drug delivery systems depend heavily on pharmaceutical excipients, which are fundamental to critical quality attributes (CQAs) like bioavailability,...

Abstract The present study aimed to develop and optimize a shikonin-loaded mucoadhesive microemulsion for intranasal delivery with the objective of...

Abstract Purpose Rheumatoid arthritis is a chronic autoimmune disease requiring long-term therapy, often limited by systemic adverse effects and inadequate...

Abstract The development of enteric multiparticulate systems requires precise control of coating architecture and release behavior to ensure consistent in...

Abstract This study presents a Quality by Design (QbD) strategy combined with Design of Experiments (DoE) to develop hybrid polymer–lipid hot-melt extruded (HME) formulations...

Control Strategy for Wurster Coating and Its Importance in Modern Drug Formulation Control Strategy for Wurster Coating plays a central...

Abstract Real-time release testing is defined in the International Council for Harmonisation of Technical Requirements for Pharmaceuticals for Human Use...

Introduction to the Formulation and Design of Multiunit Particulate Systems Formulation and design of multiunit particulate systems focus on oral...

Abstract This work focused on N-nitroso-fluoxetine, a N-nitrosamine drug substance-related impurity (NDSRI) formed in fluoxetine-containing products via nitrosation pathways. N-nitroso-fluoxetine...