Quality by Design (QbD)

Abstract Colorectal cancer (CRC) presents a significant global health challenge, where the efficacy of conventional treatments is often hampered by...

Abstract This review is presented in two parts: Part I addresses the theoretical foundations and principles of ultrasonic and acoustic...

Abstract The anti-glaucoma drug betaxolol hydrochloride (BH) exhibits poor ocular bioavailability due to limited corneal permeability, rapid precorneal loss, short...

From Milk to Medicine: 100 Years of Pharmaceutical Lactose continuous improvement For more than a century, lactose has quietly shaped...

Abstract Background: Fused deposition modeling (FDM) is one of the most well-known and often published methods for 3D-printed drug delivery systems....

Abstract SmartLipids represent the third generation of lipid-based nanocarriers, emerging as a transformative innovation in modern drug delivery and formulation...

Abstract Insufficient aqueous dissolution properties constitute a fundamental barrier impacting approximately 40% of commercialized and 90% developmental pharmaceuticals, significantly limiting...

Abstract Quality by design (QbD) and design of experiments (DoE) have become central to modern pharmaceutical development, yet most guidance...

Abstract Hydroxypropyl methylcellulose (HPMC) is commonly used to enable controlled release (CR) of an active pharmaceutical ingredient (API) from a...

Spin freeze-drying (SFD) has emerged as a potential breakthrough in pharmaceutical lyophilization. It promises over 90 % reductions in cycle time...