Quality by Design (QbD)

Abstract SmartLipids represent the third generation of lipid-based nanocarriers, emerging as a transformative innovation in modern drug delivery and formulation...

Abstract Insufficient aqueous dissolution properties constitute a fundamental barrier impacting approximately 40% of commercialized and 90% developmental pharmaceuticals, significantly limiting...

Abstract Quality by design (QbD) and design of experiments (DoE) have become central to modern pharmaceutical development, yet most guidance...

Abstract Hydroxypropyl methylcellulose (HPMC) is commonly used to enable controlled release (CR) of an active pharmaceutical ingredient (API) from a...

Spin freeze-drying (SFD) has emerged as a potential breakthrough in pharmaceutical lyophilization. It promises over 90 % reductions in cycle time...

Inertness Compritol® 888 ATO is inert Compritol® 888 ATO - glyceryl dibehenate - does not react with active pharmaceutical ingredients...

Abstract Purpose This study aims to develop an integrated control strategy using process analytical technology (PAT) and a quality by...

Abstract The present study aimed to design, optimize, and evaluate enteric-coated nanocarriers to enhance the oral bioavailability of Rifaximin, a...

Abstract Since Pfizer developed the mRNA vaccine for COVID-19 by leveraging artificial intelligence (AI) for designing the vaccine, integrating AI...

Compritol® 888 ATO: one excipient benefits all, from formulator to end-user Compritol® 888 ATO With a drug release governed by...