Quality by Design (QbD)

Softgel capsule manufacturing is one of the most challenging and sophisticated segments in the pharmaceutical and nutraceutical industries. Unlike solid...

Abstract Manufacturing co-processed pharmaceutical excipients is a great innovation in drug delivery, with improved compressibility, flowability, disintegration, and reduced moisture...

Abstract This paper exemplifies a Quality by Digital Design (QbDD) workflow for the crystallisation and isolation of active pharmaceutical ingredients...

Abstract Ribbon splitting, a phenomenon that can occur during the roller compaction operation used in dry granulation processes, can lead...

Abstract Naringenin (NRG), a citrus-derived flavonoid with antioxidant, anti-inflammatory, and anti-diabetic properties, shows promise in treating chronic diabetic wounds distinguished...

Abstract Posaconazole (PCZ) is a broad spectrum anti-fungal drug approved by FDA and currently used off-label for the treatment of...

Abstract This study investigates the use of an octenylsuccinate-modified dendrimer-like biopolymer (OS-DLB) as a carrier matrix in the formulation of...

Abstract The development of a robust oral solid dosage form requires knowledge of all the sources of variation that could...

Abstract The incorporation of poorly soluble active ingredients, which make up the majority of the molecules in development, into fixed-dose...

Abstract Quality by Design (QbD) is a transformative and systematic approach to developing top-tier pharmaceutical products, ushering in a departure...