Quality by Design (QbD)

Abstract Hydroxypropyl methylcellulose (HPMC) is commonly used to enable controlled release (CR) of an active pharmaceutical ingredient (API) from a...

Spin freeze-drying (SFD) has emerged as a potential breakthrough in pharmaceutical lyophilization. It promises over 90 % reductions in cycle time...

Inertness Compritol® 888 ATO is inert Compritol® 888 ATO - glyceryl dibehenate - does not react with active pharmaceutical ingredients...

Abstract Purpose This study aims to develop an integrated control strategy using process analytical technology (PAT) and a quality by...

Abstract The present study aimed to design, optimize, and evaluate enteric-coated nanocarriers to enhance the oral bioavailability of Rifaximin, a...

Abstract Since Pfizer developed the mRNA vaccine for COVID-19 by leveraging artificial intelligence (AI) for designing the vaccine, integrating AI...

Compritol® 888 ATO: one excipient benefits all, from formulator to end-user Compritol® 888 ATO With a drug release governed by...

Softgel capsule manufacturing is one of the most challenging and sophisticated segments in the pharmaceutical and nutraceutical industries. Unlike solid...

Abstract Manufacturing co-processed pharmaceutical excipients is a great innovation in drug delivery, with improved compressibility, flowability, disintegration, and reduced moisture...

Abstract This paper exemplifies a Quality by Digital Design (QbDD) workflow for the crystallisation and isolation of active pharmaceutical ingredients...