Solids

The absolute bioavailability of many small molecule kinase inhibitors (smKIs) is low. The reasons for low bioavailability are multifaceted and...

Solid dispersions production is one of the substantial approaches for improvement of poor drug solubility. Additionally, supercritical fluid assisted method...

Prolonged drug release provided by multiple-unit dosage forms is highly beneficial to enhance the compliance and safety of the pharmacotherapy...

Anti-HIV drug Lamivudine exhibit shorter half-life (2 h) and poor bioavailability (62% in paediatric patients), multiple dosing is required. To overcome...

Guar gum a non-ionic polysaccharide obtained from the seeds of Cyamopsis tetragonolobus of the Leguminosae family is found abundantly in...

Granulation, the process of particle enlargement by agglomeration technique, is one of the most significant unit operations in the production...

Chitosan has excellent properties, as it is nontoxic, mucoadhesive, biocompatible, and biodegradable. However, the poor water solubility of chitosan is...

Mucosal surfaces as the largest immune organ of human body cover 400 m2 of the body including the gastrointestinal, urogenital,...

Abstract Granulation is a size-enlargement process by which small particles are bonded, by means of various techniques, in coherent and...