Surfactants

Purpose In this study we evaluated the utility of in-vitro screening tools for predicting the in-vivobehavior of six cyclic peptides with different solubility...

Labrasol® ALF (Labrasol®), is a non-ionic surfactant excipient primarily used as a solubilising agent. It was investigated here as an...

Two decades since the discovery of the RNA interference (RNAi) pathway, we are now witnessing the approval of the first...

Polysorbates, a group of nonionic surfactants, are widely used as pharmaceutic excipient. Their quality and safety are closely related to...

Holistic QbD approach for hot-melt extrusion process design space evaluation: Linking materials science, experimentation and process modeling The aim of...

Permeability glycoprotein (P-gp) is a 170 kDa membrane transporter from the category of efflux pumps, which is situated at the apical...

As a biopharmaceutical classification system Class IV drug, lopinavir (LPV) shows relatively poor water solubility and permeation in vivo. In...

This study aims to develop mucoadhesive tablets containing solid lipid particles for controlled release pattern through buccal delivery. The buccal...

Hydroquinone (HQ) is an anti-hyperpigmentation agent with poor physicochemical stability. HQ formulations are currently elaborated by compounding in local pharmacies....

In this study, we develop and apply a high-throughput screening pro- tocol to investigate the activity of non-ionic surfactants, with...