Surfactants

Formulation technologies are critical for increasing the efficacy of drug products containing poorly soluble hydrophobic drugs, which compose roughly 70%...

HL235 is a new cathepsin K inhibitor designed and synthesized to treat osteoporosis. Since HL235 has poor aqueous solubility, a...

Recombinant proteins are large and complex molecules, whose therapeutic activity highly depends on their structure. Formulation of biopharmaceuticals aims at...

Aims Apelin and vitamin E have been proposed as signaling molecules, but their synergistic role is unknown. The aim of...

As you maybe aware, polysorbates present a host of challenges for stabilizing biopharmaceuticals due to their own stability issues. To...

Oral administration is the most accepted and favored route as various side effects such as fear, pain and risk of...

In this study, the abilities of hydroxypropyl methylcellulose (HPMC) and methylcellulose (MC) as nonionic surfactants to improve the dissolution rate...

Starch nanoparticles were prepared from native potato starch using acid hydrolysis and precipitation methods. The acid hydrolysis method yielded high...

Purpose In this study we evaluated the utility of in-vitro screening tools for predicting the in-vivobehavior of six cyclic peptides with different solubility...

Labrasol® ALF (Labrasol®), is a non-ionic surfactant excipient primarily used as a solubilising agent. It was investigated here as an...