Introduction

Talc has been traditionally used as an anti-tack agent in various immediate release and enteric coating formulations. However, it is subject to sedimentation and may cause system instability.  Sedimentation of talc can lead to process concerns such as gun clogging which may lead to frequent process interruptions.

Objective

To determine the feasibility of formulating a ready mixed immediate release coating system containing polymer, plasticizer, and a non-talc anti-adherent agent. .The experiments mentioned in the article demonstrate the possibility of using capric glycerides as the non-talc anti tack agent.