Characterization of Cellulose Derivatives as Pharmaceutical Excipient – Article

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Characterization of Cellulose Derivatives as Pharmaceutical Excipient
Abstract: The aim of this study was characterization and evaluation of the various pharmaceutical excipients. Cellulose derivatives like Methyl cellulose, Hydroxy propyl methyl cellulose (HPMC) and Micro crystalline cellulose (MCC) were evaluated. The characterization parameters such as bulk density, tapped density, Hausner’s ratio, Carr’s index and angle of repose were evaluated. Results revealed that Methyl Cellulose showed maximum bulk density of 0.39±0.02 g/ml while MCC showed minimum bulk density of 0.36 ±0.02 g/ml. All the polymers were found to possess a good flow property.
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