Nanotechnology is an emerging technology that can be used in a broad array of Food and Drug Administration (FDA)-regulated products, for purposes such as increasing the bioavailability of a drug. Recently, there has been an increased focus on using nanotechnology and nanomaterials in the development of novel drug delivery systems and targeted therapies. This focus is resulting in an increasing number of investigational new drug applications, new drug applications (NDAs), and abbreviated new drug applications for drug products containing nanomaterials to the FDA.