Controlled Release Excipient

Prolonged drug release provided by multiple-unit dosage forms is highly beneficial to enhance the compliance and safety of the pharmacotherapy...

Anti-HIV drug Lamivudine exhibit shorter half-life (2 h) and poor bioavailability (62% in paediatric patients), multiple dosing is required. To overcome...

Quality by Design (QbD), a current trend employed to develop and optimise various critical pharmaceutical processes, is a systematic approach...

Guar gum a non-ionic polysaccharide obtained from the seeds of Cyamopsis tetragonolobus of the Leguminosae family is found abundantly in...

Chitosan has excellent properties, as it is nontoxic, mucoadhesive, biocompatible, and biodegradable. However, the poor water solubility of chitosan is...

In this study the relationship between the viscoelasticity/mechanical properties of metronidazole-containing aqueous polymer networks composed of HEC and PVP and...

The current study investigates the development of extemporaneous preparation of hot melt extruded diclofenac sodium (Df-Na) pellets processed with glyceryl...

Content uniformity (CU) is a well-recognized challenge for low-dose direct compression (DC) tablet formulations. Using a dual particle engineering approach...

The objective of this study was to investigate the effect of binder (water-soluble vs. -insoluble) and granulation fluid (aqueous vs....

Hot-melt extrusion (HME) has gained increasing attention in the pharmaceutical industry; however, its potential in the preparation of solid self-emulsifying...