Design of Co-lyophilised Ternary Insulin-Sucrose-Polymer Systems with Enhanced Amorphous Glass stability

1. February 2026

Abstract The glass stability of lyophilized amorphous peptide formulations, intended for incorporation into solid oral dosage forms, require stabilisation against...

Protective effects of berberine-loaded chitosan/solid lipid nanoparticles in streptozotocin-induced gestational diabetes mellitus rats

13. January 2026

Abstract Berberine, known as an antioxidant agent, can improve glycemic indices in animal models of diabetes; however, it is clinically...

Impact of yeast cell wall incorporation on the mucoadhesion, stability, oral permeability and release profile of alginate/whey protein beads loaded with insulin

12. December 2025

Abstract This study aimed to evaluate the impact of incorporating yeast cell wall (YCW) into alginate/whey protein (ALG/WP) particles as...

Capryol® 90 is an efficacious intestinal absorption enhancer for insulin in vivo when combined other excipients

2. December 2025

Abstract The excipient, Capryol® 90, comprises 90 % monoesters of propylene glycol monocaprylate (C8). With a low hydrophilic lipophilic balance...

Quality by Design (QbD) Accredited Naringenin-loaded Chitosan Nanoparticles Impregnated Gel for Diabetic Wound Healing: Formulation, Optimization, In silico and In vitro Characterization

1. September 2025

Abstract Naringenin (NRG), a citrus-derived flavonoid with antioxidant, anti-inflammatory, and anti-diabetic properties, shows promise in treating chronic diabetic wounds distinguished...

Lipid-Based Formulation of Nateglinide as a Promising Strategy for Managing Solubility Challenges in Type II Diabetes Therapy: A SMEDDS Approach

3. July 2025

Abstract The present study focuses on the development and optimization of a solid self-microemulsifying drug delivery system (SSMEDDS) of Nateglinide,...

Diabetes