Hot-melt extrusion

Abstract Poor tablet hardness and drug re-crystallization are two common challenges of amorphous solid dispersion (ASD) formulations prepared with hot-melt...

Abstract Although FDM is one of the prominent 3D printing technologies, and it has been widely investigated in pharmaceutical sciences,...

Abstract Background: Three-dimensional (3D) printing has been established in pharmaceutical sciences for preparing customized dosage forms with intricate release profiles....

Abstract For young patients, medicated chocolates and medicated lollipops are quite appropriate dose forms because traditional formulations like tablets and...

This study explores a novel acid-base supersolubilization (ABS) principle for enhancing the solubility and dissolution rate of indomethacin, a poorly...

Abstract Manufacturing co-processed pharmaceutical excipients is a great innovation in drug delivery, with improved compressibility, flowability, disintegration, and reduced moisture...

Abstract Pramipexole dihydrochloride (PPX) is a Biopharmaceutical Classification System (BCS) Class I drug with a short half-life, and its aqueous...

Abstract The pharmaceutical industry is increasingly adopting co-processed excipients as alternatives to conventional excipients in tablet manufacturing despite certain regulatory...

Abstract Famotidine suffers from low oral bioavailability due to poor aqueous solubility, short half-life, and limited gastric retention. This study...

Abstract Amorphous solid dispersions (ASDs) represent a promising formulation strategy for improving the solubility and bioavailability of poorly water-soluble drugs,...