Hot-melt extrusion

Abstract This study investigates the use of an octenylsuccinate-modified dendrimer-like biopolymer (OS-DLB) as a carrier matrix in the formulation of...

Mucoadhesive vaginal films are increasingly regarded as a versatile platform for local drug delivery, offering prolonged mucosal retention, ease of...

Abstract The number of newly developed substances with poor water solubility continually increases. Therefore, specialized formulation strategies are required to...

Abstract Hot melt extrusion (HME) is a widely used method of taste masking in medication formulations, notably for bitter Active...

Abstract The development of solid dispersions (SDs) has gained increased attention in recent decades, leading to successful delivery systems for...

Abstract Amorphous solid dispersions (ASDs) make a significant contribution to enhancing the solubility of poorly soluble drugs. The incorporation of...

Abstract Aceclofenac (ACF), a Non-Steroidal Anti-Inflammatory Drug (NSAID), is formulated with Soluplus® (SOLP) to enhance solubility and bioavailability. This study...

Abstract Drug delivery products based on poly(lactic-co-glycolic acid) (PLGA) often have multiphasic drug release profiles with slow “lag phase(s)” and...

Abstract Aim: In addition to numerous benefits provided by nanosuspensions (NSs) (e.g., enhanced saturation solubility, increased area for interaction with fluids),...

Abstract The present study aims to develop capsules employing hot melt extrusion (HME) and fused deposition modeling (FDM) three-dimensional (3D)...