Hot-melt extrusion

Abstract The pharmaceutical industry is increasingly adopting co-processed excipients as alternatives to conventional excipients in tablet manufacturing despite certain regulatory...

Abstract Famotidine suffers from low oral bioavailability due to poor aqueous solubility, short half-life, and limited gastric retention. This study...

Abstract Amorphous solid dispersions (ASDs) represent a promising formulation strategy for improving the solubility and bioavailability of poorly water-soluble drugs,...

Abstract Pediatric neuropathy poses significant challenges in pain management due to the limited availability of approved pharmacological options. Gabapentin, commonly...

Abstract This study investigates the use of an octenylsuccinate-modified dendrimer-like biopolymer (OS-DLB) as a carrier matrix in the formulation of...

Mucoadhesive vaginal films are increasingly regarded as a versatile platform for local drug delivery, offering prolonged mucosal retention, ease of...

Abstract The number of newly developed substances with poor water solubility continually increases. Therefore, specialized formulation strategies are required to...

Abstract Hot melt extrusion (HME) is a widely used method of taste masking in medication formulations, notably for bitter Active...

Abstract The development of solid dispersions (SDs) has gained increased attention in recent decades, leading to successful delivery systems for...

Abstract Amorphous solid dispersions (ASDs) make a significant contribution to enhancing the solubility of poorly soluble drugs. The incorporation of...