Hot-melt extrusion

This poster has been presented at the 2026 World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical (PBP) Technology. Introduction Fused Deposition...

Abstract Background/Objectives. Warfarin possesses a bitter taste and requires a personalized dose in the range of 4.5 to 77 mg per...

Abstract Background: Fused deposition modeling (FDM) is one of the most well-known and often published methods for 3D-printed drug delivery systems....

Abstract Hydroxypropyl methylcellulose acetate succinate (HPMCAS) is commonly used to develop amorphous solid dispersions (ASDs), but its use is mostly...

Abstract 3D printing drug formulations for personalized medicine is a growing research field and offers many opportunities to improve patient...

Abstract Contemporary small-molecule drug candidates increasingly have limited aqueous solubility, rendering oral delivery challenging. Amorphous solid dispersions (ASDs) and lipid-based...

Abstract Delamanid, an antituberculosis drug used for multidrug-resistant tuberculosis, has extremely poor water solubility and a high melting point of...

Abstract Kollidon® SR of low (KoL) or high (KoH) moisture content was hot-melt extruded with sorbitol (SOR). Microhardness of KoL/SOR...

Abstract Insufficient aqueous dissolution properties constitute a fundamental barrier impacting approximately 40% of commercialized and 90% developmental pharmaceuticals, significantly limiting...

Abstract This study explores the impact of drug loading (DL) on the physical stability, dissolution performance, and micellisation behaviour of...