Hot-melt extrusion

Abstract For young patients, medicated chocolates and medicated lollipops are quite appropriate dose forms because traditional formulations like tablets and...

This study explores a novel acid-base supersolubilization (ABS) principle for enhancing the solubility and dissolution rate of indomethacin, a poorly...

Abstract Manufacturing co-processed pharmaceutical excipients is a great innovation in drug delivery, with improved compressibility, flowability, disintegration, and reduced moisture...

Abstract Pramipexole dihydrochloride (PPX) is a Biopharmaceutical Classification System (BCS) Class I drug with a short half-life, and its aqueous...

Abstract The pharmaceutical industry is increasingly adopting co-processed excipients as alternatives to conventional excipients in tablet manufacturing despite certain regulatory...

Abstract Famotidine suffers from low oral bioavailability due to poor aqueous solubility, short half-life, and limited gastric retention. This study...

Abstract Amorphous solid dispersions (ASDs) represent a promising formulation strategy for improving the solubility and bioavailability of poorly water-soluble drugs,...

Abstract Pediatric neuropathy poses significant challenges in pain management due to the limited availability of approved pharmacological options. Gabapentin, commonly...

Abstract This study investigates the use of an octenylsuccinate-modified dendrimer-like biopolymer (OS-DLB) as a carrier matrix in the formulation of...

Mucoadhesive vaginal films are increasingly regarded as a versatile platform for local drug delivery, offering prolonged mucosal retention, ease of...