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Dwell time is an important parameter responsible for the material deformation and the mechanical and biopharmaceutical properties of the tablet....
Binder selection is a crucial step in continuous twin-screw wet granulation (TSWG), as the material experiences a much shorter residence...
Only few excipients are known to be suitable as pelletization aids. In this study, the potential use of croscarmellose sodium...
The magnitude of the frictional forces during the ejection of porous pharmaceutical tablets plays an important role in determining the...
Abstract A threat to human health in developed and, in particular, in developing countries, counterfeit medicines represent the largest identified...
A set of numerical methods is described that allows predictive finite element method (FEM) simulations of the compaction of multi-component...
Fenofibrate (FNF) is used to treat hyperlipidemia. However, FNF is a poorly water-soluble drug, and the dosage of commercial products...
ABSTRACT This comprehensive review explores modern granulation techniques in pharmaceutical dosage forms along with conventional methods, focusing on dry granulation...
Abstract Forty-eight (48) drug products (DPs) containing amorphous solid dispersions (ASDs) have been approved by the U.S. Food and Drug...
Abstract The influence of hydroxypropyl cellulose type (HPC-SSL SFP, HPC-SSL), concentration (2 %, 3.5 %, 5 %) and filler (lactose, calcium hydrogen phosphate...
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