Improved Dissolution of Poorly Water-Soluble Rutin via Solid Dispersion Prepared Using a Fluid-Bed Coating System

21. December 2025

Abstract Background/Objectives: Rutin, a bioactive flavonol glycoside known for its antioxidant, anti-inflammatory, and anticancer activities, faces limited clinical application due...

poster - Application of Novel Partially Pregelatinized Cassava [tapioca] Starch as Substitute Filler-Diluent

Application of Novel Partially Pregelatinized Cassava [tapioca] Starch as Substitute Filler-Diluent to Lactose in Personalized Substance-Abuse Therapy for Lactose Intolerant Population

17. December 2025

This poster was presented at the AAPS 2025 by GRIFFIN GAMMA LLC PURPOSE A study protocol was developed to evaluate...

Understanding excipient interactions unlocks untapped potential of RNA-lipid nanoparticles in dry powder formulations for local pulmonary delivery

16. December 2025

Abstract Small interfering RNA (siRNA)-loaded lipid nanoparticles (LNPs) are a promising modality for gene silencing therapies. Pulmonary delivery offers an...

An integrated analytical approach to evaluate powder aggregation and predict the aerodynamic performance of homogeneous powders

10. December 2025

Abstract Dry Powder Inhaler (DPI) formulations generally consist of drug particles with a size between 1 and 5 µm, ideal for...

Modeling of physical-mechanical and microbiological properties of tablets made of complex fluidized bed granules containing living yeast cells using common mixing rules

19. November 2025

Abstract In order to administer probiotic microorganisms effectively, suitable dosage forms and production methods are required. These must be geared...

Predicting granule size via in-line NIR spectroscopy during fluidized bed foam granulation and drying

18. November 2025

Abstract Wet granulation-a unit operation involving mixing polymeric binders with powdered formulations-is well established in the pharmaceutical industry, playing a...

From Liquid SNEDDS to Solid SNEDDS: A Comprehensive Review of Their Development and Pharmaceutical Applications

14. November 2025

Abstract The liquid and solid formulations of self-nano-emulsifying drug delivery systems (SNEDDS) have garnered significant attention in the pharmaceutical field...

Modeling the influence of the microbial loading level of fluidized bed granules on physical–mechanical and microbiological tablet properties

13. November 2025

Abstract In order to be able to administer efficient probiotic formulations, it is necessary to process the respective microorganisms gently...

The Functional Attributes of Co-Processed Excipients in Direct Compression

12. November 2025

Abstract The pharmaceutical industry is increasingly adopting co-processed excipients as alternatives to conventional excipients in tablet manufacturing despite certain regulatory...

Influence of homolog composition and hydration states of magnesium stearate on carrier-based dry powder formulations for inhalation

9. November 2025

Abstract Magnesium stearate (MgSt) has been used as a force control agent (FCA) to enhance the aerosol performance of carrier-based...

Lactose