Lactose

How moisture management, particle engineering, flowability, and grade selection can improve formulation performance and manufacturing consistency Introduction In pharmaceutical development,...

Abstract Plant-derived materials frequently exhibit poor flowability and compactibility, complicating their conversion into solid dosage forms. This preliminary study investigated...

Abstract Ellagitannins (ETs) from Punica granatum leaves are susceptible to degradation under less acidic pH conditions, which may compromise their use as...

Abstract Although localized strain critically affects the mechanical integrity of pharmaceutical tablets, conventional macroscopic tests cannot capture spatial strain distributions....

Abstract Background/Objectives: The aim of this study was to develop and apply a novel integrated approach for predicting local mucosal tolerability...

Introduction In the realm of pharmaceutical formulations, excipients are indispensable, enhancing the safety, efficacy, stability, manufacturability, and patient acceptability of...

Abstract Liquisolid systems (LSS) represent a promising approach for improving dissolution of poorly water-soluble drugs; however, the interplay between formulation...

Abstract Background: Hypertension exhibits marked circadian variations, with an increased risk of cardiovascular events during the early morning hours. Conventional...

Abstract Lactose (LA), the primary carrier in dry powder inhalers (DPIs), often exhibits excessive drug adhesion, which impairs aerosolization. In...

Abstract Background/Objectives: Conventional SeDeM-ODT screening relies on physicochemical properties and endpoint disintegration tests, which may have limited discriminatory power among...