Lipids

Modified- or sustained-release matrices are designed to release a drug slowly over an extended period of time. Formulations must be...

High lipophilicity and poor aqueous solubility are the endemic problems of new drug molecules. Sixty to seventy percent of these...

Felodipine (FLD), a dihydropyridine calcium channel blocker with excellent antihypertensive effect, is poorly soluble and undergoes extensive hepatic metabolism, which...

Purpose: Poorly water-soluble drugs when given orally experience limited dissolution due to their low solubility in aqueous solutions. This study aimed...

Ibrutinib (IBR) is the choice of drug for the treatment of chronic lymphocytic leukaemia (CLL) and mantle cell lymphoma (MCL)....

Active pharmaceutical ingredients (APIs) exhibiting low aqueous solubility or poor intestinal permeability will be associated with poor or variable drug...

The use of amorphous drug delivery systems is an attractive approach to improve the bioavailability of low molecular weight drug...

Purpose The present work describes the systematic development of ganoderic acid (GA)–loaded solid lipid nanoparticles (SLNs) for the treatment of...

The self-generating nano-emulsifying drug delivery system (SNEDDS) is among the most effective approaches to enhance the oral bioavailability of a...

The aim of this research was the development and characterization of three gel dosage forms of Halobetasol propionate loaded lipid...