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Oral delivery of protein and peptide drugs faces immense challenges, partially due to the inherent unfavourable characteristics of the molecules...
Dissolution media based on bicarbonate buffers closely mimic the environment of intestinal fluids and thus improve in vitro in vivo...
Excipients play an important role in the formulation of dosage forms and can be used to improve the bioavailability of...
The aim of this work was to evaluate the effectiveness of mesoporous clays or silicas to develop fast-dissolving glyburide tablets...
The aim of the present paper is to study the effect of common excipients on the permeability of atenolol (as...
Disintegration is the first event in the bioavailability cascade after the ingestion of immediate release tablets. Although the influence of...
Diabetes is characterized by chronic hyperglycemia. Although metformin hydrochloride (MHCl)- and glyburide (GLB)-containing conventional tablets are available in the market...
Excipients are major components of oral solid dosage forms, and changes in their critical material attributes (excipient variability) and/or amount...
Isomalt is a polyol derived from sucrose. Advantages of this excipient are its sweet taste, which is supposed to allow...
Roll compaction/dry granulation is established in manufacturing of solid oral dosage forms and, within the context of continuous manufacturing, it...
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