Dry Powder Inhalers (DPI)

The present study documents the drug-excipient incompatibility in the physical mixtures and its influence on bulk homogeneity and flowability for...

Pulmonary drug administration has long been used for local or systemic treatment due to several advantages. Dry powder inhalers emerge...

The multi-drug resistance of Pseudomonas aeruginosa is an overwhelming cause of terminal and persistent lung infections in cystic fibrosis (CF) patients. Antimicrobial synergy has been shown...

Dry powder inhalers (DPIs) are favorable devices for the delivery of dry formulations to the lungs; still, they largely fail...

Pulmonary drug delivery is currently the focus of research and development because of its potential to produce maximum therapeutic benefit...

Spray-drying is an extensively used technology for engineering inhalable particles. Important technical hurdles are however experienced when lipid-based excipients (LBEs) are spray-dried....

The need for optimisation of DPI formulations is a main research motivation in respiratory drug delivery. Well-established formulations like carrier-based...

To overcome some of the shortfalls of the types of dissolution testing currently used for pulmonary products, a new custom-built...

A bivalent Norovirus vaccine candidate has been developed that contains Norovirus strain GI.1 Norwalk-virus like particles (VLP) and strain GII.4...

Pulmonary drug delivery can have several advantages over other administration routes, in particular when using dry powder formulations. Such dry...