Formulation development with Kollicoat Smartseal: Impact of plasticizers
How can plasticizers impact the functionality of film-coating latex-based dispersion?
When formulating a film coating, plasticizers are often required to increase polymer chain mobility, improve mechanical properties, such as elasticity and cracking resistance, and reduce the minimum film forming temperature.
The plasticizer selection and concentration are based on the plasticizing effect, similar physicochemical characteristics, desired flexibility, and compatibility with all formulation components.
However, particular attention should be paid to latex dispersions when adding this ingredient. Plasticizers can interfere with the dispersion’s stability by changing the electrostatic repulsion between particles, causing coagulation and a lack of polymer functionality.
Read the whitepaper, to understand the impact of two commonly used plasticizers on the stability of the aqueous dispersion Kollicoat® Smartseal 30 D, a film-coating polymer designed for taste-masking:
Formulation development with Kollicoat® Smartseal: impact of plasticizers
See the full whitepaper on “Kollicoat® Smartseal: Impact of plasticizers” here
(click the picture to download the whitepaper)
Source: BASF brochure “Kollicoat® Smartseal: Impact of plasticizers”
Do you need more information or a sample of excipients by BASF?
Read also the further Kollicoat® Smartseal article: