Tag: formulation

Abstract Aim Efonidipine hydrochloride ethanolate (EHE), a BCS Class II calcium channel blocker, exhibits extremely poor aqueous solubility and undergoes ...

Abstract Glioblastoma is one of the aggressive and hard-to-treat forms of brain tumor, and this is largely due to the ...

Abstract Real-time release testing is defined in the International Council for Harmonisation of Technical Requirements for Pharmaceuticals for Human Use ...

Abstract Cataract progression is closely associated with oxidative stress and inflammatory activation, while effective non-surgical interventions remain limited. Aesculetin (AES) ...

Abstract Poor aqueous solubility is a major cause of solubility-limited absorption and misleading pharmacokinetic outcomes during early oral drug discovery. ...

Abstract Background/Objectives: The aim of this study was to develop and apply a novel integrated approach for predicting local mucosal tolerability ...

Introduction In the realm of pharmaceutical formulations, excipients are indispensable, enhancing the safety, efficacy, stability, manufacturability, and patient acceptability of ...

Situation One of our customers developed 3 different dosages for 1 active pharmaceutical ingredient (API). Coating was avoided as the ...

This article is part of the “Less Known Facts About Excipients” series by Philippe Tschopp. Calcium Carbonate: A Widely used ...

Abstract Liquisolid systems (LSS) represent a promising approach for improving dissolution of poorly water-soluble drugs; however, the interplay between formulation ...