formulation

Abstract This chapter reviews data on 72 omeprazole (OME) formulations developed in the past 5 years. The types of OME formulations, the excipients and the methods are analyzed in depth. Data on 72 omeprazole (OME) formulations created over the last 5 years are reviewed in this chapter. A…
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Abstract Lung cancer ranks among the leading factors behind cancer-related fatalities across the globe. Erlotinib (ERT) is one of the frontline drugs used for lung cancer. However, ERT shows poor aqueous solubility, dissolution, gastrointestinal absorption, bioavailability, and therapeutic…
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Abstract Poloxamer 338 is used as versatile thermo-responsive gelling agent in topical and sub-cutaneous applications. Due to application specific needs a gel point below body or even below room temperature is required. The influence of inorganic salts and active pharmaceutical ingredients (APIs)…
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Abstract An improved predictive numerical index has been developed to predict the tendency of bed agglomeration in fluidized bed boilers. The index was developed based on the melt fraction resulting from the thermodynamic equilibrium model of fuel ash compositions together with SiO2 as the bed…
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Abstract Background Ritonavir is an anti-retroviral protease inhibitor to treat HIV, AIDS infections. Methods The RN-SLNs were prepared by using hot homogenization followed ultrasonication method and optimized by using a two-factor, three-level central composte design (CCD). The independent…
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Abstract Microemulsions have been commonly used with various permeation enhancers to improve permeability through the skin. The purpose of this study was to compare the release and permeation ability of two commonly used permeation enhancers—diethylene glycol monoethyl ether (DGME) and oleyl…
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Why do Mineral Salts Low in Endotoxins offer various advantages for the use in pharmaceutical and medical products and applications? Endotoxins or pyrogens are lipopolysaccharides – outer membrane components of gram-negative bacteria. During decomposition or metabolism, these bacteria release…
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Abstract Background/Objectives: Chagas disease is a neglected tropical disease caused by infection with the parasite Trypanosoma cruzi. Benznidazole and nifurtimox are the only approved drugs for treating this condition, but their low aqueous solubility may lead to erratic bioavailability. This…
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Abstract Hypothesis Water-in-water (W/W) emulsions can be obtained when two water-soluble components are mutually immiscible. The scientific literature on W/W emulsions focuses on polymer–polymer mixtures, with only a few reports on polymer-salt systems, and no documented cases involving…
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TaBlitz distinguishes itself as the only AI-powered tablet design software currently available, offering unparalleled predictive capabilities, right-first-time design principles, comprehensive database integration, and continuous improvement. Its unique position in the market, combined with…
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