Multiparticulates For Paediatric Oral Drug Delivery – Glatt Pharmaceutical Services
As the demand for pediatric dosage forms continues to increase across the industry, there can be formulation challenges for this patient population. Pediatric patients may require different dosage forms depending on age ranges, and patient compliance can be significantly impacted based on the size, swallowability, and palatability of the dosage form.
In this webinar, we discussed currently available technologies that can be used to create pediatric dosage forms, and highlight the suitability of multiparticulates for this challenging population.
You can watch the full recording of the webinar including the 40 minute presentation from Allison Labriola about multiparticulates in pediatric drug formulations here!
See some interesting questions and answers from the webinar here:
Q1: Can you comment on the relative cost of goods and costs of manufacturing for mutliparticulates compared to minitablets?
Q2: Do you see performance or quality differences in using sugar or cellulose pellets?
Q3: Do you find any difference with coating the spheres made from microcrystalline cellulose vs starch / lactose / sugar or other sphere subtrates? The MCC spheres tend to be much more expensive in comparison.
Q4: What is alternative method for taste masking assesment besides dissolution testing?
Q5: As you mentioned in the first case study about the API with low solubility and high dose, could you explain a bit more on how the multiparticulates can improve the solubility of the API?
Q6: What is the minimum dosage you achieve with the multiparticulates in capsules?