Nitrosamine

More than 80 years ago, BASF invented PVPs, and we fully understand their chemistry. We have excipients with low nitrites,...

The trace level quantification of nitrite in excipients and chemicals is of major interest to the pharmaceutical industry due to...

Abstract Drug substances and excipients must be stored in recommended storage conditions and should comply with their specifications during the...

The WHO has published a new draft guideline on considerations for the prevention and control of nitrosamine contamination in pharmaceutical...

1. Introduction The issue of Nitrosamine impurities in drug and excipient manufacturing has become a significant concern for the pharmaceutical...

PRESS RELEASE February 27, 2024, Asahi Kasei Corp. Contributing to lower risk of potentially carcinogenic nitrosamine impurities in pharmaceuticals To...

In summer 2018, drug regulatory authorities first became aware of nitrosamine impurities in a number of medicinal products, including antihypertensives in the...

N-Nitrosamines are a class of indirect acting mutagens, as their metabolic degradation leads to the formation of the DNA-alkylating diazonium...

N-nitrosamines (NAs) are a class of compounds of which many, especially of the small dialkyl type, are indirect acting DNA...

See the latest issue of Fuji Chemical Industries Technical Newsletter: It presents Fujicalin®, a low-risk solution for mitigating nitrosamine risks in...