Ocular Delivery

Abstract Cyclodextrins (CDs) are cyclic oligosaccharides made up of α-(1 → 4)-linked d-glucopyranose units and are generally obtained by enzymatic conversion of...

Abstract Cataract progression is closely associated with oxidative stress and inflammatory activation, while effective non-surgical interventions remain limited. Aesculetin (AES)...

Abstract Fungal keratitis (FK) is a leading cause of corneal blindness worldwide. Although voriconazole (VOR) is effective, its poor corneal...

Abstract The anti-glaucoma drug betaxolol hydrochloride (BH) exhibits poor ocular bioavailability due to limited corneal permeability, rapid precorneal loss, short...

Abstract Background: Rebamipide (REB) is a poorly water-soluble drug with limited ocular bioavailability, necessitating advanced delivery strategies for sustained therapy in...

Abstract The objective of this work was to prepare an ophthalmic excipient with antibacterial, antioxidant, and anti-inflammatory functions, which was...

Abstract With great anticipation, the European Medicines Agency (EMA) guideline titled “Quality and Equivalence of Locally Applied, Locally Acting Cutaneous Products” officially...

Abstract Liver diseases—encompassing hepatitis, liver fibrosis, fatty liver, and hepatocellular carcinoma—constitute a formidable global health challenge. Existing treatments are often...

Abstract This work outlines the formulation and characterization of Fenticonazoleloaded LeciPlex (FCN-LPX), adopting a simple blending technique for the eradication...

Abstract Posaconazole (PCZ) is a broad spectrum anti-fungal drug approved by FDA and currently used off-label for the treatment of...