Ocular Delivery

Abstract Linezolid (LNZ), oxazolidinone antibiotic, is widely used in clinical practice for treatment of bacterial keratitis. Despite its efficacy, the...

Abstract Pullulan, an exopolysaccharide, obtained from the fungus Aureobasidium pullulans, is a non-ionic, hydrophilic, biodegradable, biocompatible, and tolerogenic polymers that is used...

Abstract The ocular bioavailability of a drug is inadequate due to physiological constraints. In this study, an ocular film of...

High intraocular pressure (IOP) is the main risk factor for glaucoma progression. Acetazolamide (AZM) presents a potent IOP-lowering effect but...

Abstract This study evaluates the encapsulation efficiency and intraocular diffusion of astaxanthin-loaded liposomes for ophthalmic topical delivery. Liposomes were prepared...

Abstract Antibiotic eyedrops typically require frequent instillation due to the eye’s defensive mechanisms limiting drugs from reaching target sites. This...

Abstract Coenzyme Q10 (CoQ10) is a lipophilic antioxidant agent that plays a crucial role in the mitochondrial electron transport chain....

Abstract The study aims to develop new prolonged delivery systems of pilocarpine hydrochloride (pilocarpine⸱HCl) for the therapy of glaucoma. Polymer...

The purpose of this study was to improve the efficacy of olopatadine hydrochloride (OT) in treating allergic conjunctivitis (AC). To...

Abstract Background: This study introduces a novel dexamethasone (DEX) mixed micellar system (DEX-MM) using Soluplus® and Pluronic F-127 (PF127) to...