Oral Excipients

Challenges in Pre-Clinical Oral Drug Delivery Pre-clinical studies are essential for evaluating the safety, pharmacokinetics, and efficacy of drug candidates...

See the EMA Document published on 28th of January 2026  This Q&A applies to human and veterinary medicines. The document...

Abstract Background: Buccal administration offers direct access to systemic circulation, improving drug bioavailability when compared with the conventional oral route....

Oral Solid Dosage Forms (OSDFs) like tablets and capsules continue to serve as the cornerstone of pharmaceutical drug delivery, valued...

Abstract Pharmaceutical cocrystals are a well-established class of solid-state forms that can modulate the solubility, dissolution, stability, and bioavailability of...

Abstract The glass stability of lyophilized amorphous peptide formulations, intended for incorporation into solid oral dosage forms, require stabilisation against...

Abstract Low water solubility and extensive hepatic first-pass metabolism limit oral bioavailability of Nebivolol hydrochloride (NEB), a new-generation β-blocker agent...

Abstract Purpose Ustekinumab, targeting interleukin (IL)-12 and IL-23, is effective in treating chronic immune-mediated inflammatory diseases, but needs to be...

Abstract Background: ODT acetaminophen tablets are an alternative drug therapy for patients who have difficulty in swallowing tablets or capsules....

Abstract Orally disintegrating tablets (ODTs) are a solid oral dosage form designed to rapidly disintegrate in the mouth without the...