Oral Excipients

Abstract Biomacromolecules including peptides, proteins, antibodies, and gene medicines, comprise important classes of therapeutics in treating disease. A drawback of...

Abstract Four decades have elapsed since orally disintegrating tablets (ODTs) were first formulated as the emulsion/type Lyoc tablet, a porous...

Abstract This review is presented in two parts: Part I addresses the theoretical foundations and principles of ultrasonic and acoustic...

THE STRATEGIC SHIFT IN ORAL DRUG DELIVERY THE STRATEGIC SHIFT IN ORAL DRUG DELIVERY Oral administration remains the gold standard...

Abstract This study aims to develop the freeze-dried core–shell nanoparticles (nanocapsules; NCs) as an effective dosage form for improving the...

Abstract Tolcapone is a nitrocatechol-based drug used as adjuvant therapy in Parkinson’s Disease (PD). Despite being effective in managing PD-associated...

Abstract Extended-release (ER) oral formulations provide therapeutic and practical benefits for pediatric patients by minimizing fluctuations in systemic exposure, reducing...

Abstract Oral dosage form development still relies heavily on empirical trial-and-error, while the high prevalence of poorly soluble drug candidates...

Abstract Background/Objectives. Warfarin possesses a bitter taste and requires a personalized dose in the range of 4.5 to 77 mg per...

Abstract Age-appropriate oral medicines remain limited for patients with swallowing difficulties, especially children. We present a chewable, drug delivery platform...