Any excipient that can be taken through the mouth can be labelled as an oral excipient.
Pharma Excipients
Oral Excipients
Applications of Polysorbates – by KLK Kolb
KLK Kolb excipients, marketed under the Hedjuvan brand, are all produced at the Hedingen facility in Switzerland. These versatile excipients find extensive use in human, veterinary and biopharmaceutical industry. As surfactants, they play a crucial role in surface-to-surface interactions, including…
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Daily multi-segment capsule for time-tunable drug release toward enhanced polypharmacy adherence
Progress and potential
We have developed a tunable, multi-segment daily capsule to advance polypharmacy, enhance adherence to medication regimens, and improve therapeutic outcomes. The capsule design enables multiple-drug or multiple-dose delivery. Each capsule incorporates multiple compartments,…
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Design, evaluation, and in vitro–in vivo correlation of self-nanoemulsifying drug delivery systems…
Abstract
The ability to predict the absorption of exenatide (Ex), a GLP-1 analogue, after oral dosing to rats in self-nanoemulsifying drug delivery systems (SNEDDS), using in vitro methods, was assessed. Ex was complexed with soybean phosphatidylcholine (SPC) prior to loading into SNEDDS. A…
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Oral colon-targeted responsive chitosan/pectin-based nanoparticles propels the application of…
Abstract
Tofacitinib (Tof), a commercially available pan-Janus kinases inhibitor, is approved for the treatment of moderate to severe ulcerative colitis. However, its clinical application is limited due to dose-dependent systemic side effects. The present study aims to develop an efficient oral…
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Pediatric Formulation Optimization Using a Rational Design: Exploring Amorphous Solid Dispersion…
Abstract
Developing orally administered pediatric formulations presents significant challenges due to the unique characteristics of pediatric patients. Terbinafine hydrochloride (TER), a powerful antifungal agent, is effective against various fungal infections, including Tinea capitis, which is…
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Applications of Sorbitan Esters – by KLK Kolb
KLK Kolb excipients, marketed under the Hedjuvan brand, are all produced at the Hedingen facility in Switzerland. These versatile excipients find extensive use in human, veterinary and biopharmaceutical industry. As surfactants, they play a crucial role in surface-to-surface interactions, including…
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Alginate coated mesoporous silica nanoparticles as oral delivery carrier of curcumin and quercetin…
Abstract
The synergistic bioactive effect of polyphenols can enhance the development of functional foods to prevent chronic diseases such as cancer. Curcumin and quercetin have been shown to possess anticancer properties. The combination of curcumin and quercetin has been shown to provide…
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Fundamentals and future trends of 3D printing in drug delivery
Fundamentals and future trends of 3D printing in drug delivery
See the new book, edited by Dimitrios A. Lamprou and Dimitrios G. Fatouros. This book provides an in-depth discussion on key factors affecting the printing process such as different printer technologies, materials selection,…
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Ritonavir loaded solid lipid nanoparticles for oral drug delivery and bioavailability enhancement
Abstract
Background
Ritonavir is an anti-retroviral protease inhibitor to treat HIV, AIDS infections.
Methods
The RN-SLNs were prepared by using hot homogenization followed ultrasonication method and optimized by using a two-factor, three-level central composte design (CCD). The independent…
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Decades of expertise in the field of application technology – The Product Development (PD)…
IOI Oleo GmbH is known for its high-quality oleochemical specialities and the technical advice it provides on the use of its products. Thanks to its diversity and longstanding reliability, the product portfolio is used in the pharmaceutical, care, nutrition and technical applications sectors. The…
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