Oral Excipients

Abstract Poor aqueous solubility is a major cause of solubility-limited absorption and misleading pharmacokinetic outcomes during early oral drug discovery....

Abstract Poor aqueous solubility limits the in vitro dissolution performance of many drugs, among them curcumin which is a bioactive...

This article is part of the “Less Known Facts About Excipients” series by Philippe Tschopp. Gum Arabic Excipient: Origin, Structure,...

Understanding patient attitudes and preferences has become an essential part of modern therapeutic decision making. The effectiveness of therapies doesn’t...

The exclusivity period and subsequent loss of exclusivity (LOE) are critical points in the lifecycle of any drug, particularly for...

New formulation strategies are beginning to yield clinically and commercially viable oral biological therapies, according to a Lonza whitepaper published...

Abstract Press-coated tablets (PCTs) are a modern dosage form designed to circumvent the negative effects of liquid and heat exposure...

Abstract The oral delivery of biologics such as oligonucleotides may be enabled by the use of a chemical permeation enhancer...

Influence of Water on the Structure of MCC Influence of Water on the Structure of MCC describes how moisture reshapes...

Lipid-based excipients from IOI Oleo help to improve the bioavailability of poorly soluble active ingredients. The majority of new active...