Orally Dissolving Technology Excipient

Abstract The in-person workshop “Drug Dissolution in Oral Drug Absorption” was held on May 23–24, 2023, in Baltimore, MD, USA. The workshop was organized into lectures and breakout sessions. Three common topics that were re-visited by various lecturers were amorphous solid dispersions (ASDs),…
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Abstract The aim of this systematic review was to identify and critically appraise the available evidence regarding solid oral dosage forms (SODFs), e.g., tablets, and challenges regarding the oral administration of medicine to inpatients in a variety of healthcare settings such as (1) hospitals,…
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Abstract In this study, orally disintegrating tablets (ODT) of pramipexole dihydrochloride monohydrate (PPX) was developed with direct compression method by using ready-to-use excipients Parteck® ODT, Pharmaburst® 500, Ludiflash®, F Melt®, and Prosolv® Easytab SP for pediatric restless leg syndrome…
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Abstract In this work, concentration prediction models applicable to a very wide range of concentrations for personalized tablet manufacturing were developed using near-infrared (NIR) spectroscopy. Tablet manufacturing experiments were conducted, and NIR spectral data of the tablets were obtained.…
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Abstract Background: Prednisolone is a corticosteroid with a very bitter taste acts as anti- anti-inflammatory and immune suppressant drug and it is used at any age. Objective: To improve patient compliance by masking the bitter taste of the drug to be delivered as an orodispersible tablet.…
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Self-microemulsifying drug delivery systems (SMEDDS) are lipid-based formulations, designed to improve the solubility of poorly-water soluble drugs. Mesoporous silica is frequently used for SMEDDS solidification by various techniques. One of them is wet granulation, which enables achieving both high…
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ABSTRACT Oral administration of medicine is one of the most common delivery routes still in use today. Various dosage forms are administered via the oral route including tablets, capsules, syrups, solutions and emulsions. Tablets constitute a large part of orally available dosage forms due to ease…
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A multi-national online survey was developed to obtain feedback on users’ experiences of administration devices for oral and inhaled paediatric medicines. The questionnaire was divided into two identical parts: 1) for caregivers looking after children aged 0–18 years, and 2) for children aged 10 …
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Type 2 diabetes mellitus (T2DM) is a metabolic disorder characterized by persistent hyperglycaemia with significant morbidity and mortality rates. Currently, metformin is a drug used as first-line therapy during the management of T2DM patients. Despite metformin's effectiveness and potency in…
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In the past few decades, texture analysis (TA) has gained importance as a valuable method for the characterization of solid oral dosage forms. As a result, an increasing number of scientific publications describe the textural methods that evaluate the extremely diverse category of solid…
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