Pharma Excipients
Cellulose
New Excipient For Oral Drug Delivery: CNC Derived From Sugarcane Bagasse-Derived Microcrystalline…
Abstract
Nanocrystalline cellulose (CNC) has emerged as a subject of researcher’s interest because of its diverse attributes encompassing biocompatibility, sustainability, a high aspect ratio, and an abundance of −OH groups suitable for modifications. Sugarcane bagasse microcrystalline cellulose…
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Nordic Bioproducts Group opens its first major production facility for advanced cellulosic materials
PRESS RELEASE
April 24th, 2024
Finnish startup Nordic Bioproducts Group has opened its state-of-the-art production facility in Lappeenranta, Finland. This facility, powered by the company’s proprietary AaltoCellTM Technology, is dedicated to the commercial-scale production of advanced…
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Alternative For Prohibited Food Additive TiO2
The discussion about the excipient titanium dioxide in the European food industry is already several years old. TiO2 was banned from food products in the EU and other countries since 2022 as being maybe carcinogenic . This even had consequences for the pharmaceutical industry. Several suppliers now…
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Solid implantable devices for sustained drug delivery
Implantable drug delivery systems (IDDS) are an attractive alternative to conventional drug administration routes. Oral and injectable drug administration are the most common routes for drug delivery providing peaks of drug concentrations in blood after administration followed by concentration decay…
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Role of additives in starch-based edible films and coating: A review with current knowledge
Edible films and coating provide a potentially effective method for preserving fresh food products by reducing moisture loss, regulating respiration rate, improving surface smoothness, and or preventing microbial growth during their storage. Concurrently, starch has proven for its inexpensive,…
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High-performance nanomesh-structured cellulose as a versatile pharmaceutical excipient
Biocompatible cellulose has been used as a pharmaceutical excipient for several decades. However, there are still shortcomings, such as low drug loading, slow disintegration, and easy drug extraction. Herein, we describe a novel process for manufacturing cellulose nanomesh (CNM), a new structured…
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Polymeric Systems for the Controlled Release of Flavonoids
Flavonoids are natural compounds that are attracting great interest in the biomedical field thanks to the wide spectrum of their biological properties. Their employment as anticancer, anti-inflammatory, and antidiabetic drugs, as well as for many other pharmacological applications, is extensively…
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The Future of Drug Delivery
Drug delivery technologies have been proven to improve treatment outcomes in many ways, including enhancing therapeutic efficacy, reducing toxicity, increasing patient compliance, and enabling entirely new medical treatments. As the therapeutic landscape has evolved from small-molecule drugs to a…
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Natural Biopolymers as Smart Coating Materials of Mesoporous Silica Nanoparticles for Drug Delivery
In recent years, the functionalization of mesoporous silica nanoparticles (MSNs) with different types of responsive pore gatekeepers have shown great potential for the formulation of drug delivery systems (DDS) with minimal premature leakage and site-specific controlled release. New…
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Design and Development of Fluconazole-Loaded Nanocellulose-Eudragit Vaginal Drug Delivery System
Purpose
The purpose of this research work was to evaluate the scaffolds of rice and wheat nanocellulose with Eudragit E100 for vaginal delivery of fluconazole.
Method
The nanocellulose-based scaffolds were fabricated by the lyophilization technique using a two-factor three-level central…
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