Pharma Excipients
Cellulose
Size-dependent filling effect of crystalline celluloses in structural engineering of composite…
Oleogels are a class of solid-fat mimetics that contain a large fraction of oil. Most of these materials have low stiffness and poor oil-binding capacity at commercially viable concentrations, which limits their application in the food and cosmetic industries. To improve their mechanical behavior,…
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Influence of commonly used excipients on the chemical degradation of enalapril maleate in its solid…
The physicochemical stability of enalapril maleate was investigated in the presence of fourteen different excipients divided into four different classes. The extent of a drug-excipient interaction was investigated by following the chemical stability using HPLC. It was found that there is a certain…
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Production and Characterization of Cellulose Nanofiber Slurries and Sheets for Biomedical…
Cellulose nanomaterials are produced employing a multitude of methodologies including electrospinning, bacterial generation, acid digestion, and a variety of mechanical defibrillation techniques; the morphology of the nanomaterial produced is specific to the production process. Feedstocks range from…
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Spherical Cellulose Micro and Nanoparticles: A Review of Recent Developments and Applications
Cellulose, the most abundant natural polymer, is a versatile polysaccharide that is being exploited to manufacture innovative blends, composites, and hybrid materials in the form of membranes, films, coatings, hydrogels, and foams, as well as particles at the micro and nano scales. The application…
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Preliminary study for the development of potent hydrogels for local drug delivery applications
Currently, design and development of formulations for the oral cavity and local application is a rather challenging process since the components should be non-irritant and provide relief. Hydrogels-based drug delivery systems have been proposed as suitable candidates for oral mucosal (eg, buccal,…
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Cellulose derivatives as effective recrystallization inhibitor for ternary ritonavir solid…
Amorphous solid dispersions (ASDs) are regarded as one of the most promising techniques for poorly-soluble active pharmaceutical ingredients (API). However, the thermodynamic instability of ASDs at supersaturated state makes them easy to recrystallize in aqueous media.
In this study, ritonavir…
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Design, optimization and pharmacokinetic evaluation of Piribedil loaded solid lipid nanoparticles…
Piribedil (PBD) is an anti-Parkinson’s drug that gained interest recently due to its unique pharmacological profile. But its clinical use is severely limited by drug delivery issues like high dosing frequency (up to 5 tablets/day), low oral bioavailability (<10%), severe GI side-effects, etc. In…
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The pourability of ARBOCEL® products!
JRS cellulose products come in various shapes and structures.
For their customers, it is not only essential, to receive excellent functionality in their applications, but also to understand how they can incorporate the fibers in their production lines.
In large scale processes, parameters like…
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Topical cellulose nanocrystals-stabilized nanoemulgel loaded with ciprofloxacin HCl with enhanced…
Spray-dried cellulose nanocrystals (CNC) were investigated as a potential stabilizer for the preparation of nanoemulsion gels (nanoemulgels) loaded with ciprofloxacin hydrochloride to act as dual-role gels capable of stimulating the tissue regeneration as well as inhibition of microbial growth.…
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Biotemplated Hollow Mesoporous Silica Particles as Efficient Carriers for Drug Delivery
We designed three types of hollow-shaped porous silica materials via a three-step biotemplate-directed method: porous hollow silica nanorods, hollow dendritic fibrous nanostructured silica (DFNS), and ultraporous sponge-like DFNS. The first step was making a biotemplate, for which we used cellulose…
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