Pharma Excipients
Modified Starch
In-line monitoring of powder blend homogeneity in continuous drug manufacture using near infrared…
The pharmaceutical industry faces technical challenges in the near future when transitioning from the traditional batch wise manufacturing to continuous manufacturing.
One issue that needs to be solved is how to obtain high-quality measurements of a moving solid powder sample. The aim of this…
Read More...
Read More...
Current Developments in Excipient Science – Implication of Quantitative Selection of Each…
Implication of Quantitative Selection of Each Excipient in Product Development
Excipients’ role in designing different dosage forms does not require any introduction. These are the additives that are added to the formulation along with pharmacologically active substance. The main purpose of adding…
Read More...
Read More...
In vitro drug release from acetylated high amylose starch-zein films for oral colon-specific drug…
This study describes the preparation of free films of zein with and without acetylated high amylose maize starch (HAS) and their corresponding coated tablets as a novel approach to colonic drug delivery. We hypothesise that the embedding of a digestible starch component within the inert zein would…
Read More...
Read More...
Combined Approach of Cyclodextrin Complexation and Nanostructured Lipid Carriers for the Development…
The development of specific and age-appropriate pediatric formulations is essential to assure that all children and their care-givers can easily access to safe and effective dosage forms. The need for developing specific pediatric medicinal products has been highlighted by the European Medicines…
Read More...
Read More...
Application of natural polymers as pharmaceutical excipients
The use of natural polymer as excipients in pharmaceutical sector is expanding day by day. Low cost, safety degradable are the main causes that make them differ from other sources. Natural sources have wide range of varieties and characteristics. So they can be used…
Read More...
Read More...
Methodology to estimate the break force of pharmaceutical tablets with curved faces under…
This paper develops a methodology to estimate the break force of curved faced tablets under diametrical compression. Common excipients used in pharmaceutical tablet formulations, including microcrystalline cellulose, calcium phosphate and mannitol as well as their mixtures were characterised.…
Read More...
Read More...
Comparison of co-processed starches prepared by 3 different methods
08. November 2017
Abstract
Co-processing is currently of interest in the generation of high-functionality excipients for tablet formulation. In the present study, comparative analysis of the powder and tableting properties of three co-processed starches prepared by…
Read More...
Read More...
An explorative analysis of process and formulation variables affecting comilling in a vibrational…
31. May 2017
Abstract
Praziquantel, a BCS II class anthelmintic drug used for the treatment of schistosome infections, was coground in a vibrational mill with different polymers (linear and crosslinked povidone, copovidone and sodium starch glycolate). An explorative…
Read More...
Read More...
Structure, functionality and applications of debranched starch: A review
26. March 2017
Background
Starchy products have been widely used in the food, paper, textile, plastic, cosmetics, adhesives, and pharmaceutical industries. To meet specific requirements of their applications, different modification techniques, such as physical,…
Read More...
Read More...
Functional Assessment of Four Types of Disintegrants and their Effect on the Spironolactone Release…
16. February 2017
Abstract
Spironolactone is a drug derived from sterols that exhibits an incomplete oral absorption due to its low water solubility and slow dissolution rate. In this study, formulations of spironolactone with four disintegrants named as…
Read More...
Read More...