Paediatric

See the new book, edited by Mine Orlu, Fang Liu Provides a better understanding on the EMA reflection paper on pharmaceutical development for older patients Details reasons for applying advanced pharmaceutical technologies for the benefit of the ageing population Discusses Advanced…
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See the new book, edited by Mine Orlu, Fang Liu Provides a better understanding on the EMA reflection paper on pharmaceutical development for older patients Details reasons for applying advanced pharmaceutical technologies for the benefit of the ageing population Discusses Advanced…
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Abstract Temozolomide (TMZ) is part of the therapeutic armamentarium used in managing pediatric cancers; however, available oral forms (capsules) are not adapted for use in children. Our aim was to assess the dose accuracy and stability of TMZ using capsule contents mixed with food compared with a…
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Patient compliance and personalized dose adjustments are important factors, especially in pediatric care. Orodispersible tablets (ODTs) are gaining importance as they increase patient compliance compared to other solid oral dosage forms. ODTs are solid dosage forms that disintegrate within seconds…
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Abstract The goal of the present work was to develop an in vitro toolbox to evaluate the oral administration of dosage forms to children of different age groups and under different administration conditions (fasted/fed). Based on current data on the gastrointestinal physiology of children, a set of…
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ABSTRACT Introduction Medication errors during drug manipulations in pediatric care pose significant challenges to patient safety and optimal medication management. Epidemiological studies have revealed a high prevalenceof medication errors throughout the medication process. Due to the lack of…
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The paediatric population is composed of several very diferent subgroups, each with its own specifc characteristics. For this reason, children cannot be considered “small adults”. The development of formulations suitable for children is a complex process, as it must consider the physiological…
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This article shows the content of a poster which was presented at the 𝗘𝗨𝗣𝗳𝗜 𝗰𝗼𝗻𝗳𝗲𝗿𝗲𝗻𝗰𝗲 𝗶𝗻 𝗚𝗹𝗮𝘀𝗴𝗼𝘄 2023 Introduction BCS class II drugs show a low solubility. Modern paediatric formulations are needed to obtain high acceptance of patients at recommended daily doses Hot-melt extrusion (HME)…
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This article shows the content of a poster which was presented at the 𝗘𝗨𝗣𝗳𝗜 𝗰𝗼𝗻𝗳𝗲𝗿𝗲𝗻𝗰𝗲 𝗶𝗻 𝗚𝗹𝗮𝘀𝗴𝗼𝘄 2023 Malaria & Treatment Challenges Children aged under 5 years are the worst affected by malaria, causing about 10 % of all children’s deaths in regions where malaria is endemic. Fixed dose…
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A cross sectional pan-India study about use of administration devices for paediatric oral and inhalation medicines was conducted with a diverse pool of participants of various age groups. Via 634 respondents from more than 15 states in India, this study has identified the administration devices…
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