Paediatric

Abstract Although solid oral dosage forms are widely used in adult drug therapy, age-appropriate formulations for pediatric patients remain limited....

Abstract In the pediatric patient group, there is a constant need for individualized dosage forms with precise and adjustable drug...

Abstract The lack of age-appropriate dosage forms forces a heavy reliance on pediatric extemporaneous compounding, increasing risks of excipient-related toxicity...

Abstract In vitro compatibility assessments are a valuable tool for the early identification of potential drug–vehicle interactions. To standardize such evaluations,...

Abstract BACKGROUND The pediatric drug development landscape has experienced major shifts, largely in response to legislative and regulatory initiatives. However,...

Introduction The primary reason children refuse medicine is taste. Bitterness, astringency, and metallic aftertaste cause patients to stop taking their...

Abstract This study aimed to develop an innovative pediatric-friendly fixed-dose combination (FDC) of omeprazole (OMZ) and domperidone (DOM) for the...

Abstract Extended-release (ER) oral formulations provide therapeutic and practical benefits for pediatric patients by minimizing fluctuations in systemic exposure, reducing...

Abstract Age-appropriate oral medicines remain limited for patients with swallowing difficulties, especially children. We present a chewable, drug delivery platform...

Abstract Medication adherence remains a significant challenge in healthcare, particularly in paediatric populations, where non-adherence has a substantial impact on...