Poloxamer

Amphiphilic, non-ionic block copolymers suitable for diverse pharmaceutical applications Did you know? Kolliphor® P grade poloxamers are among the most...

Abstract Entacapone is a catechol-O-methyltransferase (COMT) inhibitor, widely used for the symptomatic treatment of Parkinson’s disease. However, it presents setbacks...

Abstract Curcumin has been widely reported to exhibit anticancer potential; however, its clinical application is limited by poor aqueous solubility...

Abstract Cannabidiol (CBD) is a non-psychoactive compound derived from Cannabis sativa. It has attracted significant attention for its anti-inflammatory, pain-relieving, and...

CARBOWAX™ SENTRY™ Polyethylene Glycols (PEGs), CARBOWAX™ SENTRY™ Methoxypolyethylene Glycols (MPEGs), and VERSENE™ NA Edetate Disodium are among the most versatile...

Abstract The taste of a drug formulation, especially of orodispersible and liquid dosage forms, is of crucial importance due to...

Abstract Poloxamer-based hydrogels, composed of thermoreversible triblock copolymers, are promising drug delivery systems due to their ability to transition from...

Abstract Background: Rebamipide (REB) is a poorly water-soluble drug with limited ocular bioavailability, necessitating advanced delivery strategies for sustained therapy in...

Abstract Macrophages, as cells of the innate immune response, are involved in the pathology of various medical conditions (tumors, intracellular...

Abstract Hydroxypropyl methylcellulose acetate succinate (HPMCAS) is commonly used to develop amorphous solid dispersions (ASDs), but its use is mostly...