Improving Tableting Performance of Lactose Monohydrate by Fluid-Bed Melt Granulation Co-Processing

Particle size distribution of co-processed mixtures, LMH and Ludipress®

Improving Tableting Performance of Lactose Monohydrate by Fluid-Bed Melt Granulation Co-Processing

22. December 2021

Co-processing is commonly used approach to improve functional characteristics of pharmaceutical excipients to become suitable for tablet production by direct...

Fig. 1: Data analysis of t50 % (Y1) (A) externally studentized residual plot; (B) predicted vs. actual plot; (C) contour plot and (D) response surface plot

Development of Sustained Release Eudragit Based Matrix Tablet of Fluvastatin Sodium Microspheres

15. December 2021

The purpose of this research is to investigate the suitability of acquiring improved dissolution profile and sustained release of Fluvastatin...

Are lipid nanoparticles really superior? A holistic proof of concept study

2. December 2021

Lipid nanoparticles are a successful carrier system for dermal drug delivery. They possess various beneficial properties, i.e., increased chemical stability...

Data-Enriched Edible Pharmaceuticals (DEEP) with Bespoke Design, Dose and Drug Release

10. November 2021

Data-enriched edible pharmaceuticals (DEEP) is an approach to obtain personalized medicine, in terms of flexible and precise drug doses, while...

Showing the solubility behavior of PE in various vehicles like surfactant (A), co-surfactants (B), and oils (C). Ternary phase diagram of PE SNEDDS formulation (D). Red covered area in ternary phase diagram represents the experimental domains for BBD. Values are given as mean ± SD (n = 3).

Development of Piperine-Loaded Solid Self-Nanoemulsifying Drug Delivery System: Optimization, In-Vitro, Ex-Vivo, and In-Vivo Evaluation

5. November 2021

Hypertension is a cardiovascular disease that needs long-term medication. Oral delivery is the most common route for the administration of...

Formulation and In Vivo Evaluation of a Solid Self-Emulsifying Drug Delivery System Using Oily Liquid Tocotrienols as Model Active Substance

26. October 2021

Self-emulsifying drug delivery systems (SEDDS) can improve the oral bioavailability of poorly water-soluble drugs. Solid self-emulsifying drug delivery systems (s-SEDDS)...

Biologic excipients: Importance of clinical awareness of inactive ingredients

14. October 2021

Due to the complexity and fragility of biological drug products, several challenges exist in their formulation development. Excipients are added...

graphical abstract of Gastroretentive Technologies in Tandem with Controlled-Release Strategies: A Potent Answer to Oral Drug Bioavailability and Patient Compliance Implications

Gastroretentive Technologies in Tandem with Controlled-Release Strategies: A Potent Answer to Oral Drug Bioavailability and Patient Compliance Implications

7. October 2021

There have been many efforts to improve oral drug bioavailability and therapeutic efficacy and patient compliance. A variety of controlled-release...

graphical abstract of Formulation design, production and characterisation of solid lipid nanoparticles (SLN) and nanostructured lipid carriers (NLC) for the encapsulation of a model hydrophobic active

Formulation design, production and characterisation of solid lipid nanoparticles (SLN) and nanostructured lipid carriers (NLC) for the encapsulation of a model hydrophobic active

7. September 2021

Lipid nanoparticles have been widely investigated for their use as either carriers for poorly water soluble actives or as (Pickering)...

Surfactants influence polymer nanoparticle fate within the brain

1. September 2021

Drug delivery to the brain is limited by poor penetration of pharmaceutical agents across the blood-brain barrier (BBB), within the...

Poloxamer

Improving Tableting Performance of Lactose Monohydrate by Fluid-Bed Melt Granulation Co-Processing

Development of Sustained Release Eudragit Based Matrix Tablet of Fluvastatin Sodium Microspheres

Are lipid nanoparticles really superior? A holistic proof of concept study

Data-Enriched Edible Pharmaceuticals (DEEP) with Bespoke Design, Dose and Drug Release

Development of Piperine-Loaded Solid Self-Nanoemulsifying Drug Delivery System: Optimization, In-Vitro, Ex-Vivo, and In-Vivo Evaluation

Formulation and In Vivo Evaluation of a Solid Self-Emulsifying Drug Delivery System Using Oily Liquid Tocotrienols as Model Active Substance

Biologic excipients: Importance of clinical awareness of inactive ingredients

Gastroretentive Technologies in Tandem with Controlled-Release Strategies: A Potent Answer to Oral Drug Bioavailability and Patient Compliance Implications

Formulation design, production and characterisation of solid lipid nanoparticles (SLN) and nanostructured lipid carriers (NLC) for the encapsulation of a model hydrophobic active

Surfactants influence polymer nanoparticle fate within the brain

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