Polymers

Abstract The glass stability of lyophilized amorphous peptide formulations, intended for incorporation into solid oral dosage forms, require stabilisation against...

Highlights PLGA/PBAE coordinates endosomal escape and timely mRNA release in APCs PLGA/PBAE enhances mRNA transfection in APCs and promotes immune...

Abstract Alectinib (ALB) is a kinase inhibitor typically used for patients with anaplastic lymphoma kinase (ALK)-positive non-small cell lung cancer....

Abstract A key challenge in topical drug delivery is the inherently low bioavailability of many active compounds within skin tissue....

We previously demonstrated the use of near-infrared (NIR) imaging to evaluate differences in disintegration for various capsule formulations after oral...

Abstract The development of safer treatment alternatives for cancer and other chronic illnesses still calls for innovation. Chemopreventive agents (e.g.,...

Abstract Background/Objectives: The growing threat posed by antimicrobial resistance to worldwide public health highlights the urgent need not only for new...

Abstract The concurrent rise of autoimmune diseases, which affect nearly 10% of the global population, along with allergic conditions such as...

Abstract Drug adherence in pediatrics can be challenging due to bitter drug taste, dysphagia and polypharmacy. With pediatric hypertension on...

Objective Polymeric microspheres (MS) have been developed with moderate success using aqueous emulsification (AqE) for small molecules and peptides with...